Søgeord (urin) valgt.
11 emner vises.
1
FDA Approves New Antibiotic for Uncomplicated UTIs
Medscape Infectious Diseases, 27.04.2024
Tilføjet 27.04.2024
The US Food and Drug Administration has approved pivmecillinam (Pivya) tablets to treat uncomplicated urinary tract infections in women. Medscape Medical News
Læs mere
2
Contact tracing management of a measles case in a paediatric hospital: experience of the local public health unit, Portugal, January 2024
Daniel Saldanha Resendes, António Tomás, Mariana Pinção Cardoso, Sebastian von Schreeb, Rita Miranda Ferrão, Paula Vasconcelos, Maria Helena Almeida, Bruno Novo Castro, Vasco Ricoca Peixoto, Renato Lourenço Silva and Margarida de Morais
Eurosurveillance latest updates, 26.04.2024
Tilføjet 26.04.2024
In January 2024, a child was diagnosed with measles in a paediatric hospital in Lisbon. Of 123 contacts, 39 (32%) were not fully immunised, presenting a risk for a potential outbreak. The public health unit initiated control measures and identified challenges during the response, such as the lack of interoperability between information systems and accessing vaccination records. The lessons learned prompted changes to national contact tracing procedures for measles, further strengthening Portugal’s preparedness.
Læs mere
3
Can D-Mannose Prevent Recurrent Urinary Tract Infection?
Medscape Infectious Diseases, 24.04.2024
Tilføjet 24.04.2024
The global rise in antibiotic resistance has complicated the therapeutic choices for urinary tract infections. Medscape Medical News
Læs mere
4
Multiple introductions of monkeypox virus to Ireland during the international mpox outbreak, May 2022 to October 2023
Gabriel Gonzalez, Michael Carr, Tomás M Kelleher, Emer O’Byrne, Weronika Banka, Brian Keogan, Charlene Bennett, Geraldine Franzoni, Patrice Keane, Cliona Kenna, Luke W Meredith, Nicola Fletcher, Jose Maria Urtasun-Elizari, Jonathan Dean, Ciaran Browne, Fiona Lyons, Brendan Crowley, Derval Igoe, Eve Robinson, Greg Martin, Jeff Connell, Cillian F De Gascun and Daniel Hare
Eurosurveillance latest updates, 19.04.2024
Tilføjet 19.04.2024
BackgroundMpox, caused by monkeypox virus (MPXV), was considered a rare zoonotic disease before May 2022, when a global epidemic of cases in non-endemic countries led to the declaration of a Public Health Emergency of International Concern. Cases of mpox in Ireland, a country without previous mpox reports, could reflect extended local transmission or multiple epidemiological introductions. AimTo elucidate the origins and molecular characteristics of MPXV circulating in Ireland between May 2022 and October 2023. MethodsWhole genome sequencing of MPXV from 75% of all Irish mpox cases (182/242) was performed and compared to sequences retrieved from public databases (n = 3,362). Bayesian approaches were used to infer divergence time between sequences from different subclades and evaluate putative importation events from other countries. ResultsOf 242 detected mpox cases, 99% were males (median age: 35 years; range: 15–60). All 182 analysed genomes were assigned to Clade IIb and, presence of 12 distinguishable subclades suggests multiple introductions into Ireland. Estimation of time to divergence of subclades further supports the hypothesis for multiple importation events from numerous countries, indicative of extended and sustained international spread of mpox. Further analysis of sequences revealed that 92% of nucleotide mutations were from cytosine to thymine (or from guanine to adenine), leading to a high number of non-synonymous mutations across subclades; mutations associated with tecovirimat resistance were not observed. ConclusionWe provide insights into the international transmission dynamics supporting multiple introductions of MPXV into Ireland. Such information supported the implementation of evidence-informed public health control measures.
Læs mere
5
Increased reports of measles in the Metropolitan City of Milan, northern Italy, September 2023 to March 2024
Maria Gori, Clara Fappani, Silvia Bianchi, Sabrina Senatore, Daniela Colzani, Priscilla Pasutto, Melissa Baggieri, Silvia Gioacchini, Antonella Marchi, Paola Bucci, Emilio D’Ugo, Marino Faccini, Danilo Cereda, Luigi Vezzosi, Elisabetta Tanzi, Fabio Magurano and Antonella Amendola
Eurosurveillance latest updates, 19.04.2024
Tilføjet 19.04.2024
Since late 2023, the Metropolitan City of Milan and surrounding areas (northern Italy) have been experiencing a resurgence of measles, with most cases detected starting from January 2024. During this brief period, we observed measles in travellers from endemic areas, participants in international events, vaccinees and healthcare workers. Indigenous cases have also been identified. Even though we have not yet identified large and disruptive outbreaks, strengthening surveillance and vaccination activities is pivotal to help limit the impact of measles spread.
Læs mere
6
How Can Doctors Best Assess Worsening Dengue Cases?
Medscape Infectious Diseases, 18.04.2024
Tilføjet 18.04.2024
It is important to inform patients about warning signs such as abdominal pain, repeated vomiting, decreased urine output, or dizziness when standing, says an epidemiologist. Medscape Infectious Diseases
Læs mere
7
Emergence of OXA-48-like producing Citrobacter species, Germany, 2011 to 2022
Julian Sommer, Hannah Reiter, Janko Sattler, Elisabetta Cacace, Jessica Eisfeld, Sören Gatermann, Axel Hamprecht and Stephan Göttig
Eurosurveillance latest updates, 12.04.2024
Tilføjet 12.04.2024
BackgroundCarbapenemase-producing Enterobacterales are a public health threat worldwide and OXA-48 is the most prevalent carbapenemase in Germany and western Europe. However, the molecular epidemiology of OXA-48 in species other than Escherichia coli and Klebsiella pneumoniae remains poorly understood. AimTo analyse the molecular epidemiology of OXA-48 and OXA-48-like carbapenemases in Citrobacter species (spp.) in Germany between 2011 and 2022. MethodsData of 26,822 Enterobacterales isolates sent to the National Reference Centre (NRC) for Gram-negative bacteria were evaluated. Ninety-one Citrobacter isolates from 40 German hospitals harbouring blaOXA-48/OXA-48‑like were analysed by whole genome sequencing and conjugation experiments. ResultsThe frequency of OXA-48 in Citrobacter freundii (CF) has increased steadily since 2011 and is now the most prevalent carbapenemase in this species in Germany. Among 91 in-depth analysed Citrobacter spp. isolates, CF (n = 73) and C. koseri (n = 8) were the most common species and OXA-48 was the most common variant (n = 77), followed by OXA-162 (n = 11) and OXA‑181 (n = 3). Forty percent of the isolates belonged to only two sequence types (ST19 and ST22), while most other STs were singletons. The plasmids harbouring blaOXA‑48 and blaOXA-162 belonged to the plasmid types IncL (n = 85) or IncF (n = 3), and plasmids harbouring blaOXA‑181 to IncX3 (n = 3). Three IncL plasmid clusters (57/85 IncL plasmids) were identified, which were highly transferable in contrast to sporadic plasmids. ConclusionIn CF in Germany, OXA-48 is the predominant carbapenemase. Dissemination is likely due to distinct highly transmissible plasmids harbouring blaOXA‑48 or blaOXA-48-like and the spread of the high-risk clonal lineages ST19 and ST22.
Læs mere
8
Excess mortality in Europe coincides with peaks of COVID-19, influenza and respiratory syncytial virus (RSV), November 2023 to February 2024
Sarah K Nørgaard, Jens Nielsen, Anne Christine Nordholm, Lukas Richter, Alena Chalupka, Natalia Bustos Sierra, Toon Braeye, Maria Athanasiadou, Theodore Lytras, Gleb Denissov, Oskari Luomala, Anne Fouillet, Isabelle Pontais, Matthias an der Heiden, Benedikt Zacher, Alina Weigel, Ivo Foppa, Kassiani Gkolfinopoulou, Ioannis Panagoulias, Anna Paldy, Tibor Malnasi, Lisa Domegan, Eva Kelly, Naama Rotem, Oksana Rakhlin, Francesca K de'Donato, Chiara Di Blasi, Patrick Hoffmann, Telma Velez, Kathleen England, Neville Calleja, Liselotte van Asten, Femke Jongenotter, Ana Paula Rodrigues, Susana Silva, Petra Klepac, Diana Gomez-Barroso, Inmaculada Leon Gomez, Ilias Galanis, Ahmed Farah, Rolf Weitkunat, Katarina Fehst, Nick Andrews, Tom Clare, Declan T Bradley, Mark G O'Doherty, Naoma William, Mark Hamilton, Bolette Søborg, Tyra G Krause, Nick Bundle and Lasse S Vestergaard
Eurosurveillance latest updates, 12.04.2024
Tilføjet 12.04.2024
Since the end of November 2023, the European Mortality Monitoring Network (EuroMOMO) has observed excess mortality in Europe. During weeks 48 2023–6 2024, preliminary results show a substantially increased rate of 95.3 (95% CI: 91.7–98.9) excess all-cause deaths per 100,000 person-years for all ages. This excess mortality is seen in adults aged 45 years and older, and coincides with widespread presence of COVID-19, influenza and respiratory syncytial virus (RSV) observed in many European countries during the 2023/24 winter season.
Læs mere
9
COVID-19 Vaccination Coverage - World Health Organization African Region, 2021-2023
Morbidity and Mortality Weekly Report (MMWR), 12.04.2024
Tilføjet 12.04.2024
This report describes COVID-19 vaccination coverage in the World Health Organization African Region during 2021-2023.
Læs mere
10
Measles - United States, January 1, 2020-March 28, 2024
Morbidity and Mortality Weekly Report (MMWR), 12.04.2024
Tilføjet 12.04.2024
This report describes measles cases in the United States during 2020-2024
Læs mere
11
Recurrent UTI Patients Find Long-Term Ally in Oral Vaccine
Medscape Infectious Diseases, 9.04.2024
Tilføjet 9.04.2024
A vaccine for urinary tract infection is effective for up to 9 years and can resolve cases in which antibiotics have failed. Medscape News UK
Læs mere