Søgning på udtrykket 'sepsis' giver 63 resultater
Dokumenter [4] Sider [4] Kalender [13] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [+20]
Dokumenter [4]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock. Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf På vegne af Dansk Selskab for Infektionsmedicin: Lars Skov Dalgaard, Michael Dalager, Christian Philip Fischer, Rikke Krogh-Madsen, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
For infektionsmedicinsk interesserede yngre læger
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Sider [4]
… Thomas Benfield og Andreas Knudsen . Sekundær immundefekt: Søren Jensen-Fangel (tovholder), Christian Philip Fischer, Marie Helleberg, Jannik Helweg-Larsen, Lykke Larsen, Daria Podlekareva, Line Dahlerup Rasmussen, Pernille Ravn Sepsis: Rikke Krogh-Madsen (tovholder), Lars Skov Dalgaard, Michael Dalager Pedersen, Christian Philip Fischer, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft. Sepsis guideline, Sepsis flowchart, …
…rsus 2026: Sted Infektionsmedicinsk afd. 8632, Rigshospitalet Delkursusledelse Marie Helleberg og Trine Mogensen Program Kan downloades her Tidligere kurser 30. og 31. januar 2023 25. og 26. januar 2017 Infektionshygiejne/profylakse, sepsis og urogenitale infektioner: Dato for næste kursus 11. og 12. juni 2024: Sted Hvidovre Hospital Delkursusledelse Rikke Krogh-Madsen og Michael Dalager-Pedersen Tidligere kurser 8. og 9. juni 2021 15. og 16. maj 2018 Kardiopulmo…
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre. Artiklen "afliver" det noget forældede SIRS begreb. Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement: "Circulatory shock" N Engl J Med. 2013;369(18):1726-34 "Resuscitation fluids" N Engl J Med. 2013;369(13):1243-51 "Ventilator-induced lung injury" N Engl J Med. 2013;369(22):2126-36
Professor Niels Obel kommenterer: Denne artikel er tankevækkende - fordi vi nu igen står i en situation, hvor noget, vi mente var en "sepsis-sandhed" fra et randomiseret trial, ser ud til at være forkert.
Kalender [13]
25. april, Online
11. juni 2024, Hvidovre Hospital
21. april 2021, Online
3. maj 2019, Hindsgavl, Middelfart
1. marts 2019, Novo Nordisk Fonden, Tuborg Havnevej 19, 2900 Hellerup
5. september 2018, Online
15. maj 2018, Aarhus Universitetshospital
4. april 2017, Auditorium 1, Rigshospitalet
8. september 2016, Online
11. marts 2015, Auditorium 2, Rigshospitalet
9. oktober 2014, Aarhus
18. april 2013, Aarhus
11. april 2013, Hvidovre Hospital
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?BMC Infectious Diseases
25.11.2023
. Abstract. . Background. Sepsis in low-birth-weight neonates remains one of the most significant causes of neonatal morbidity and mortality. Approximately 3 million newborns suffer from sepsis globally every year. The aim of this study was to compare demographic and clinical features, as well as etiology and antibiotic susceptibility, of the main pathogens related to neonatal sepsis in two neonatal intensive units during a…
BMC Infectious Diseases
25.11.2023
. Abstract. . Background. Sepsis in low-birth-weight neonates remains one of the most significant causes of neonatal morbidity and mortality. Approximately 3 million newborns suffer from sepsis globally every year. The aim of this study was to compare demographic and clinical features, as well as etiology and antibiotic susceptibility, of the main pathogens related to neonatal sepsis in two neonatal intensive units during a…
Critical Care Medicine
17.11.2023
Objective: . Sepsis is a leading cause of mortality. Predicting outcomes is challenging and few biomarkers perform well. Defects in the renin–angiotensin system (RAS) can predict clinical outcomes in sepsis and may outperform traditional biomarkers. We postulated that RAS dysfunction (elevated active renin, angiotensin 1-7 [Ang-(1-7)], and angiotensin-converting enzyme 2 (ACE2) activity with depressed Ang-II and ACE activity) would be associated with mortality in a cohort of septic patients. Design: . P…
Journal of the American Medical Association
15.11.2023
To the Editor The MERCY randomized clinical trial in critically ill patients with sepsis found that the meropenem dosing strategy (continuous infusion vs intermittent bolus) did not improve the composite outcome of mortality and emergence of drug-resistant bacteria. However, we are concerned that the population for whom the administration of meropenem as a continuous infusion is expected to be most beneficial was not well represented in the trial.
Journal of the American Medical Association
15.11.2023
In Reply Augmented kidney clearance (defined as a GFR ≥130 mL/min/1.73 m2) may increase meropenem clearance, resulting in a lower chance of achieving a target plasma concentration with a bolus administration. Augmented kidney clearance occurs in approximately 20% of patients with critical illness, especially in younger patients, in those with burns, and during the first week of hospital admission. None of these circumstances were frequent in the MERCY trial; patients were older (mean age, 64 years) and ma…
Critical Care Explorations
11.11.2023
OBJECTIVES: . To identify opportunities for improving hospital-based sepsis care and to inform an ongoing statewide quality improvement initiative in Michigan. DESIGN: . Surveys on hospital sepsis processes, including a self-assessment of practices using a 3-point Likert scale, were administered to 51 hospitals participating in the Michigan Hospital Medicine Safety Consortium, a Collaborative Quality Initiative sponsored by Blue Cross Blue Shield of Michigan, at two time points (2020, 2022). Forty-eight h…
Critical Care Explorations
11.11.2023
OBJECTIVES: . Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) may accelerate bloodstream clearance of immunogenic bacterial lipids and improve sepsis outcomes. DESIGN: . Genetic and clinical epidemiology, and experimental models. SETTING: . Human genetics cohorts, secondary analysi…
Journal of the American Medical Association
11.11.2023
…istration of vasopressor agents; norepinephrine is generally preferred as an initial agent. In those cases in which cardiac output is felt to be low enough to compromise perfusion, inotropic agents may be used. In this context, use of β-blockers may well be regarded as counterintuitive inasmuch as their hemodynamic effects would tend to decrease arterial pressure and cardiac output. Despite this, investigators have challenged conventional wisdom and evaluated the effects of β-blockade for treating sepsis.
Journal of the American Medical Association
11.11.2023
This Viewpoint discusses Hospital Sepsis Program Core Elements, a set of guidance provided by the Centers for Disease Control and Prevention to help hospitals develop multiprofessional programs that monitor and optimize management and outcomes of sepsis.
BMC Infectious Diseases
9.11.2023
. Abstract. . Background. In recent years, observational studies have been conducted to investigate the potential impact of vitamins on sepsis. However, many of these studies have produced inconsistent results. Our Mendelian randomization (MR) study aims to evaluate the causality between vitamins and sepsis from a genetic perspective. . . . Methods. …
BMC Infectious Diseases
9.11.2023
. Abstract. . Background. In recent years, observational studies have been conducted to investigate the potential impact of vitamins on sepsis. However, many of these studies have produced inconsistent results. Our Mendelian randomization (MR) study aims to evaluate the causality between vitamins and sepsis from a genetic perspective. . . . Methods. …
Critical Care Medicine
9.11.2023
Objectives: . Although delirium is well described in patients with sepsis, there are limited data on other neurologic complications. We aimed to systematically review the prevalence, neuromonitoring tools, and neurocognitive outcomes in sepsis patients with neurologic complications. Data Sources: . MEDLINE and six other databases (Embase, Web of Science, Cochrane CENTRAL, and ClinicalTrials.gov) were searched through January 2023. Study Selection: . Studies of adult patients with sepsis reported neurolog…
PLoS One Infectious Diseases
9.11.2023
by Wencong Ding, Laping Huang, Yifeng Wu, Junwei Su, Liu He, Zhongxiang Tang, Min Zhang . Pyroptosis is a new form of programmed cell death recognized as crucial in developing sepsis. However, there is limited research on the mechanism of pyroptosis-related genes in sepsis-related from the Gene Expression Omnibus (GEO) database and standardized. The expression levels of pyroptosis-related genes were extracted, and differential expression analysis was conducted. A prediction model was constructed using rand…
BMC Infectious Diseases
7.11.2023
. Abstract. . Background. In recent years, observational studies have been conducted to investigate the potential impact of vitamins on sepsis. However, many of these studies have produced inconsistent results. Our Mendelian randomization (MR) study aims to evaluate the causality between vitamins and sepsis from a genetic perspective. . . . Methods. …
Critical Care Explorations
4.11.2023
BACKGROUND: . Sepsis is a common and deadly syndrome, accounting for more than 11 million deaths annually. To mature a deeper understanding of the host and pathogen mechanisms contributing to poor outcomes in sepsis, and thereby possibly inform new therapeutic targets, sophisticated, and expensive biorepositories are typically required. We propose that remnant biospecimens are an alternative for mechanistic sepsis research, although the viability and scientific value of such remnants are unknown. METHODS A…
Clinical Microbiology and Infection
1.11.2023
Antimicrobial resistance (AMR) is firmly lodged in the medical community’s collective mind as a challenge to be reckoned with in the decades to come (1). It already affects millions of lives around the globe and has been likened to climate change both in likely impact and complexity(2). The population group bearing much of the brunt of the changing bacterial landscape is perhaps less obvious.
BMC Infectious Diseases
1.11.2023
. Abstract. . Background. The generalizability of the Surviving Sepsis Campaign (SSC) guidelines to various patient populations and hospital settings has been debated. A quantitative assessment of the diversity and representation in the clinical evidence supporting the guidelines would help evaluate the generalizability of the recommendations and identify strategic research goals and priorities. In this study, we evaluated t…
Critical Care Medicine
1.11.2023
Objectives: . Echocardiography is commonly used for hemodynamic assessment in sepsis, but data regarding its association with outcome are conflicting. The aim of this study was to evaluate the association between echocardiography and outcomes in patients with septic shock using the Medical Information Mart for Intensive Care IV database. Design: . Retrospective cohort study comparing patients who did or did not undergo transthoracic echocardiography within the first 5 days of admission for the primary out…
Lancet Respiratory Medicine
31.10.2023
Molecular phenotypes previously identified in ARDS are also identifiable in multiple sepsis cohorts and respond differently to activated protein C. Molecular phenotypes could represent a treatable trait in critical illness beyond the patient's syndromic diagnosis.
PLoS One Infectious Diseases
30.10.2023
…e leads to approximately 530 deaths with a €24 million financial burden annually. This study estimated the impact of procalcitonin-guided antibiotic stewardship programs to reduce antibiotic consumption versus standard of care in patients with suspected sepsis. A decision analytic tree modelled health and budget outcomes of procalcitonin-guided antibiotic stewardship programs for patients admitted to the intensive care unit (ICU). A literature search, a survey with local clinical experts, and national dat…
Aktuelle smitsomme sygdomme [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?Morbidity and Mortality Weekly Report (MMWR)
22.09.2023
This report describes sepsis-related date rates among adults 65 years and older.
Medscape Infectious Diseases
13.09.2023
Medscape spoke with CDC contributors Raymund Dantes, MD, MPH, and Hallie Prescott, MD, MSc, about the new Hospital Sepsis Program Core Elements to help clinicians improve outcomes from sepsis. . CDC Expert Commentary
Medscape Infectious Diseases
1.09.2023
While 73% of US hospitals have sepsis teams, only 55% of them report that their team leaders get dedicated time to manage the programs for a medical emergency that affects at least 1.7 million people. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
25.08.2023
This report describes sepsis programs in hospitals and identifies areas of opportunities to improve sepsis programs.
Medscape Infectious Diseases
5.07.2023
Compared with influenza and sepsis, severe COVID-19 infections resulted in similar risk for neurological and cardiovascular conditions, suggesting a common need for long-term support. . Medscape Medical News
Medscape Infectious Diseases
1.07.2023
A new review provides insights into intravenous fluid therapy for sepsis, including how much to give at each stage of treatment. . Medscape Medical News
Medscape Infectious Diseases
6.10.2022
Experts expressed hope that, with additional research, the new testing method could eventually cut the time for sepsis detection from days to hours, potentially saving lives. .
Medscape Infectious Diseases
7.01.2022
Rates of resistance to ampicillin-gentamicin are extremely high in low- and middle-income countries. .
Medscape Infectious Diseases
24.06.2021
A sepsis-prediction model used widely by hospitals and health systems in the United States performed poorly in predicting sepsis onset in an external validation study.
Morbidity and Mortality Weekly Report (MMWR)
13.06.2019
Whole genome sequencing indicated a potential common source of bacterial contamination among four cases of septic transfusion reactions occurring in three states.
Fatal Sepsis Associated with Bacterial Contamination of Platelets ” Utah and California, August 2017
Morbidity and Mortality Weekly Report (MMWR)
28.06.2018
Morbidity and Mortality Weekly Report (MMWR)
22.09.2023
This report describes sepsis-related date rates among adults 65 years and older.
Medscape Infectious Diseases
13.09.2023
Medscape spoke with CDC contributors Raymund Dantes, MD, MPH, and Hallie Prescott, MD, MSc, about the new Hospital Sepsis Program Core Elements to help clinicians improve outcomes from sepsis. . CDC Expert Commentary
Eurosurveillance latest updates
8.09.2023
…e group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).
Medscape Infectious Diseases
1.09.2023
While 73% of US hospitals have sepsis teams, only 55% of them report that their team leaders get dedicated time to manage the programs for a medical emergency that affects at least 1.7 million people. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
25.08.2023
This report describes sepsis programs in hospitals and identifies areas of opportunities to improve sepsis programs.
Medscape Infectious Diseases
5.07.2023
Compared with influenza and sepsis, severe COVID-19 infections resulted in similar risk for neurological and cardiovascular conditions, suggesting a common need for long-term support. . Medscape Medical News
Medscape Infectious Diseases
1.07.2023
A new review provides insights into intravenous fluid therapy for sepsis, including how much to give at each stage of treatment. . Medscape Medical News
Eurosurveillance latest updates
2.06.2023
We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3–5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infections in 2022 and 2023 (8/496; 1.6%, seven associated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.
ProMED
2.06.2023
Enterovirus -- FranceSituation at a glance---------------------On [5 May 2023], France reported an increase in cases of severe neonatal sepsis associated with Enterovirus (Echovirus-11 (E-11)). A total of 9 cases of neonatal sepsis with hepatic impairment and multi-organ failure were reported between [July 2022] and [April 2023] from 4 hospitals in 3 regions of France. As of [5 May 2023], 7 cases have died and 2 were still hospitalized in neonatal unit. The current increase in incidence and severity in