Søgning på udtrykket 'sepsis' giver 70 resultater
Dokumenter [7]
Sider [6]
Kalender [15]
Nyt fra tidsskrifterne [+20]
Aktuelle smitsomme sygdomme [+20]
Dokumenter [7]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock.
Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
På vegne af Dansk Selskab for Infektionsmedicin: Lars Skov Dalgaard, Michael Dalager, Christian Philip Fischer, Rikke Krogh-Madsen, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
Rekommandationer for profylakse og vaccination ved aspleni.
Denne vejledning dækker anbefalinger omhandlende vaccinationer, antibiotika profylakse og patientinformation om generelle forholdsregler for at beskytte personer med aspleni mod infektioner.
Version 1.2, 22.10.2024. Ændringer siden version 1.1:
Vaccination mod Haemophilus influenzae ændret til 1 dosis (fejlagtigt angivet 3 doser).
Menveo beskytter efter 1 dosis (fejlagtigt angivet som nødvendigt med 2. dosis efter 2-3 mdr).
Link til bila…
For infektionsmedicinsk interesserede yngre læger
Om bl.a. svære infektioner, sepsis, infektioner hos neutropene samt etiske dilemmaer i infektionsmedicin
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Rekommandationer for profylakse og vaccination ved aspleni.
Denne vejledning dækker anbefalinger omhandlende vaccinationer, antibiotika profylakse og patientinformation om generelle forholdsregler for at beskytte personer med aspleni mod infektioner.
Version 1.1, 11.06.2024. Ændringer siden version 1: Apexxnar er ændret til Prevenar 20 (og PCV13 til Prevenar 13). Prevenar 20 kan gives allerede fra 6 måneders alderen, hvorfor denne erstatter primær vaccination med PCV13 og PPV23. Erythrocyt morfologi…
Sider [6]
…fektionsepidemiologi, SSI.
15.15 – 15.30.
Kaffe og kage og frugt.
15.30 – 16.30.
.
Antimicrobial stewardship i praksis.
Afdelingslæge, Jon Gitz Holler, Nordsjællands Hospital.
12. juni 2024 (dag 2):
Sepsis, antibiotika, urinvejsinfektioner.
Tid.
Emne og underviser.
08.30 – 12.30.
SEPSIS.
08.30 – 09.30.
Det septiske shock.
Professor, overlæge Anders Perner, Intensiv, RH.
09.30 – 09.…
…
Rationel antibiotikaanvendelse:
Trine Langfeldt Hagen (tovholder), Shakil Shakar, Susanna Deutch, Kristina Öbrinck, Mathias Hertz, Isik Johansen, Christian Kraef, Jon Gitz Holler, Mette Vang Larsen, Thomas Benfield og Andreas Knudsen .
Sepsis:
Rikke Krogh-Madsen (tovholder), Lars Skov Dalgaard, Michael Dalager Pedersen, Christian Philip Fischer, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
Sepsis guideline,
Sepsis flowchart,
…
…rsus
2026:
Sted
Infektionsmedicinsk afd. 8632, Rigshospitalet
Delkursusledelse
Marie Helleberg og Trine Mogensen
Program
Kan downloades her
Tidligere kurser
30. og 31. januar 2023
25. og 26. januar 2017
Infektionshygiejne/profylakse, sepsis og urogenitale infektioner:
Dato for næste kursus
2027:
Program
Kan ses her
Sted
Hvidovre Hospital
Delkursusledelse
Rikke Krogh-Madsen og Michael Dalager-Pedersen
Tidligere kurser
11. og 12. juni 2024
8. og 9. juni 2021
15. og 16. ma…
Risikoen for bakteriel infektion og sepsis er svært forhøjet ved manglende miltfunktion som følge af splenektomi samt kongenit eller funktionel aspleni. Alvorlige infektioner skyldes primært Streptococcus pneumoniae, Haemophilus influenzae og Neisseria meningitidis.
Risikoen for svær infektion ved malaria og dyrebid er også markant forhøjet.
Vaccination, antibiotika profylakse/tidlig behandling og adækvat patient information er afgørende for forebyggelse af infektioner.
Antibiotika behandlin…
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre.
Artiklen "afliver" det noget forældede SIRS begreb.
Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement:
"Circulatory shock" N Engl J Med. 2013;369(18):1726-34
"Resuscitation fluids" N Engl J Med. 2013;369(13):1243-51
"Ventilator-induced lung injury" N Engl J Med. 2013;369(22):2126-36
Professor Niels Obel kommenterer: Denne artikel er tankevækkende - fordi vi nu igen står i en situation, hvor noget, vi mente var en "sepsis-sandhed" fra et randomiseret trial, ser ud til at være forkert.
Kalender [15]
11. juni, Hvidovre Hospital
3. maj 2019, Hindsgavl, Middelfart
1. marts 2019, Novo Nordisk Fonden, Tuborg Havnevej 19, 2900 Hellerup
5. september 2018, Online
15. maj 2018, Aarhus Universitetshospital
4. april 2017, Auditorium 1, Rigshospitalet
8. september 2016, Online
11. marts 2015, Auditorium 2, Rigshospitalet
11. april 2013, Hvidovre Hospital
Nyt fra tidsskrifterne [+20]
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Virulence
21.10.2024
Volume 15, Issue 1, December 2024 .
Critical Care Medicine
21.10.2024
Objectives: . Refine the administrative data definition of sepsis in hospitalized patients, including less severe cases. Design and Setting: . For each of 1928 infection and 108 organ dysfunction codes used in Canadian hospital abstracts, experts reached consensus on the likelihood that it could relate to sepsis. We developed a new algorithm, called AlgorithmL, that requires at least one infection and one organ dysfunction code adjudicated as likely or very likely to be related to sepsis. AlgorithmL was c…
PLoS One Infectious Diseases
19.10.2024
…njananun, Monruedee Sukprasansap, Tewin Tencomnao, Pattarin Tangtanatakul, Asada Leelahavanichkul . Introduction Despite the well-established effects of aging on brain function and gut dysbiosis (an imbalance in gut microbiota), the influence of aging on sepsis-associated encephalopathy (SAE) and the role of probiotics in this context remain less understood. Methods C57BL/6J mice (8-week-old) were subcutaneously administered with 8 weeks of D-galactose (D-gal) or phosphate buffer solution (PBS) for aging …
BMC Infectious Diseases
11.10.2024
. Abstract. . Background. The impact of liver fibrosis on the clinical outcomes of patients with sepsis-induced coagulopathy (SIC) is not well understood. This study aimed to evaluate the association between liver fibrosis scores and in-hospital mortality in SIC patients. . . . Methods. In this retrospective observational cohort study, data …
BMC Infectious Diseases
8.10.2024
. Abstract. . Background & objective. The Infectious Disease Society of America guidelines recommend vancomycin trough levels of 15–20 mg/L for severe methicillin-resistant Staphylococcus aureus. However, recent consensus guidelines of four infectious disease organizations no longer recommend vancomycin dosing using minimum serum trough concentrations. Therefore, this study aimed to evaluate the impact of low (
BMC Infectious Diseases
3.10.2024
…nce (IR) and the prognosis of septic patients remains unclear. This study aims to investigate the correlation between the clinical subphenotype of IR represented by the triglyceride-glucose (TyG) index trajectory and the mortality rate among patients with sepsis. . . . Methods. In this retrospective cohort study, we utilized data from septic patients within the Medical Information Mart for Intensive Care (MIMIC)-IV database…
BMC Infectious Diseases
2.10.2024
…nce (IR) and the prognosis of septic patients remains unclear. This study aims to investigate the correlation between the clinical subphenotype of IR represented by the triglyceride-glucose (TyG) index trajectory and the mortality rate among patients with sepsis. . . . Methods. In this retrospective cohort study, we utilized data from septic patients within the Medical Information Mart for Intensive Care (MIMIC)-IV database…
PLoS One Infectious Diseases
1.10.2024
by Chu-Yun Liu, Yu-Shen Yang, Meng-Qin Pei, He-fan He . The objective of this study was to explore the potential causalities of fat mass, nonfat mass and height (henceforth, ‘anthropometric measures’) with sepsis risk and mortality. We conducted the Mendelian randomization (MR) investigation using genome-wide association study (GWAS) summary statistics of anthropometric measures, sepsis, and sepsis mortality. The GWAS summary data from the UK Biobank was used. Firstly, MR analysis was performed to esti…
PLoS One Infectious Diseases
27.09.2024
by Per Venge, Christer Peterson, Shengyuan Xu, Anders Larsson, Joakim Johansson, Jonas Tydén . Introduction Sepsis is a growing problem worldwide and associated with high mortality and morbidity. The early and accurate diagnosis and effective supportive therapy are critical for combating mortality. The aim of the study was to compare the kinetics of four biomarkers in plasma in patients admitted to ICU including sepsis and during antibiotics treatment. Methods The biomarkers evaluated were HBP (Heparin-b…
Journal of Medical Virology
26.09.2024
Journal of Medical Virology, Volume 96, Issue 10, October 2024.
Critical Care Medicine
20.09.2024
Objectives: . To determine the frequency of and risk factors for increased post-sepsis healthcare utilization compared with pre-sepsis healthcare utilization. Design: . Retrospective observational cohort study. Setting: . Years 2016–2019 MarketScan Commercial and Medicaid Database. Patients: . Children (0–18 yr) with sepsis treated in a U.S. hospital. Interventions: . None. Measurements and Main Results: . We measured the frequency of and risk factors for increased healthcare utilization in the 90…
Critical Care Medicine
20.09.2024
Objectives: . To characterize associations between race/ethnicity/sex, time-to-antibiotics, and mortality in patients with suspected sepsis or septic shock. Design: . Retrospective cohort study, with race/ethnicity/sex as the exposure, and time-to-antibiotics (relative to emergency department arrival) and in-hospital mortality as the outcome. Setting: . Five Massachusetts hospitals. Patients: . Forty-nine thousand six hundred nine adults admitted 2015–2022 with suspected sepsis or septic shock (blood …
Critical Care Medicine
20.09.2024
Objectives: . Pediatric sepsis-associated acute kidney injury (AKI) often requires continuous renal replacement therapy (CRRT), but limited data exist regarding patient characteristics and outcomes. We aimed to describe these features, including the impact of possible dialytrauma (i.e., vasoactive requirement, negative fluid balance) on outcomes, and contrast them to nonseptic patients in an international cohort of children and young adults receiving CRRT. Design: . A secondary analysis of Worldwide Explo…
PLoS One Infectious Diseases
17.09.2024
by Daniel Geleta, Gemeda Abebe, Tsion Tilahun, Didimos Gezahegn, Netsanet Workneh, Getenet Beyene . Background Epidemiological profiles and the rundown crisis of antimicrobial resistance from bacterial isolates in neonatal sepsis compel regular surveillance to enhance data-driven decision-making. Accordingly, this study aimed to assess the phenotypic epidemiology and antimicrobial resistance profiles of bacteria isolated from clinically suspected neonatal sepsis in Ethiopia. Methods A total of 342 neonate…
Critical Care Explorations
16.09.2024
OBJECTIVES: . It is suggested that sepsis may be classified into four clinical phenotypes, using an algorithm employing 29 admission parameters. We applied a simplified phenotyping algorithm among patients with bacterial sepsis and severe COVID-19 and assessed characteristics and outcomes of the derived phenotypes. DESIGN: . Retrospective analysis of data from prospective clinical studies. SETTING: . Greek ICUs and Internal Medicine departments. PATIENTS AND INTERVENTIONS: . We analyzed 1498 patients, 6…
BMJ Open
13.09.2024
. Objectives. Understanding the burden of disease of sepsis is essential for monitoring the effectiveness of international strategies to improve sepsis care. Our objective was to describe the multinational trend of sepsis-related mortality for the period 1985–2019 from the WHO Mortality Database. . Design. Retrospective analysis of the WHO Mortality Database. . Setting. We included data from all countries defined by the WHO as having ‘high usability data’ and at least 10 years of total available dat…
Journal of Infectious Diseases
12.09.2024
…nduced brain injury.Methods . We measured serum levels of GFAP and UCH-L1 retrospectively in serum samples from three study populations: 1) human cases infected with Venezuelan equine encephalitis virus (VEEV) and Madariaga virus (MADV) (n = 73), 2) human sepsis patients who were severely ill or diagnosed with encephalitis (n = 66), and 3) sepsis cases that were subsequently evaluated for cognitive impairment (n = 64).Results . In the virus infection group, we found elevated GFAP for VEEV (p = 0.014) and MA…
Current Opinion in Infectious Diseases
11.09.2024
…nting for sepsis evaluations need to be treated empirically with acyclovir to capture one case of neonatal HSV. Clinical and laboratory risk factors for neonatal HSV identified in the literature can be used for a targeted approach to testing and treating infants for HSV to optimize resource utilization. Summary . The literature supports a targeted approach to evaluation and empiric acyclovir treatment for neonatal HSV, but additional studies are needed to validate this approach given the rarity of disease.
Journal of the American Medical Association
11.09.2024
Before they can determine the pathogens causing sepsis in patients and treat them with a targeted antibiotic, clinicians must wait for the results of a blood culture test, which can often take 2 to 3 days. Now an ultra-rapid test in development that eliminates the need for blood culture may provide same-day answers, according to a study published in Nature.
Infection
8.09.2024
… . . Methods. We present a literature review and report the case of a 39-year-old female diagnosed with common variable immunodeficiency (CVID) with IgG and IgA deficiency suffering from a sepsis with L. mirabilis. As no fully closed L. mirabilis genome besides the type strain was available to date, we additionally performed complete genome sequencing of L. mirabilis. . . . Results. …
Aktuelle smitsomme sygdomme [+20]
Der er mere end 20 resultater, måske du vil se
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Medscape Infectious Diseases
1.08.2024
A meta-analysis found that sepsis alert systems were associated with improved patient outcomes and adherence to sepsis management protocols in emergency departments. . Medscape Medical News
Medscape Infectious Diseases
12.07.2024
Urine culture-negative patients with bacteremia had the highest rate of ICU admission and representation following discharge and the longest hospital stay, reported a study. . Medscape Medical News
Medscape Infectious Diseases
17.06.2024
Delays in antibiotic administration increased the mortality risk by threefold in children with sepsis presenting to the ED. . Medscape Medical News
Medscape Infectious Diseases
15.04.2024
The first-ever AI diagnostic tool for sepsis was granted marketing authorization through the FDA's De Novo pathway. . Medscape Medical News
Medscape Infectious Diseases
1.02.2024
Based on new findings, the task force now suggests that pediatric sepsis be defined by a Phoenix Sepsis Score of at least 2 points in children with suspected infection. . MDedge News
Morbidity and Mortality Weekly Report (MMWR)
22.09.2023
This report describes sepsis-related date rates among adults 65 years and older.
Medscape Infectious Diseases
13.09.2023
Medscape spoke with CDC contributors Raymund Dantes, MD, MPH, and Hallie Prescott, MD, MSc, about the new Hospital Sepsis Program Core Elements to help clinicians improve outcomes from sepsis. . CDC Expert Commentary
Medscape Infectious Diseases
1.09.2023
While 73% of US hospitals have sepsis teams, only 55% of them report that their team leaders get dedicated time to manage the programs for a medical emergency that affects at least 1.7 million people. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
25.08.2023
This report describes sepsis programs in hospitals and identifies areas of opportunities to improve sepsis programs.
Medscape Infectious Diseases
5.07.2023
Compared with influenza and sepsis, severe COVID-19 infections resulted in similar risk for neurological and cardiovascular conditions, suggesting a common need for long-term support. . Medscape Medical News
Medscape Infectious Diseases
1.07.2023
A new review provides insights into intravenous fluid therapy for sepsis, including how much to give at each stage of treatment. . Medscape Medical News
Medscape Infectious Diseases
6.10.2022
Experts expressed hope that, with additional research, the new testing method could eventually cut the time for sepsis detection from days to hours, potentially saving lives. .
Medscape Infectious Diseases
7.01.2022
Rates of resistance to ampicillin-gentamicin are extremely high in low- and middle-income countries. .
Medscape Infectious Diseases
24.06.2021
A sepsis-prediction model used widely by hospitals and health systems in the United States performed poorly in predicting sepsis onset in an external validation study.
Morbidity and Mortality Weekly Report (MMWR)
13.06.2019
Whole genome sequencing indicated a potential common source of bacterial contamination among four cases of septic transfusion reactions occurring in three states.
Morbidity and Mortality Weekly Report (MMWR)
28.06.2018
Eurosurveillance latest updates
5.10.2024
…young children was reported by several countries. Viral infections including influenza and varicella, known risk factors for iGAS infection, also increased. . . Aim. To estimate the proportion of GAS skin and soft tissue infections (SSTI) and pneumonia/sepsis in children (≤ 5 years) attributable to varicella, and the proportion of GAS pneumonia/sepsis in children and adults attributable to potentially predisposing respiratory viruses influenza A and B, RSV, hMPV and SARS-CoV-2 in the Netherlands. . …
Medscape Infectious Diseases
1.08.2024
A meta-analysis found that sepsis alert systems were associated with improved patient outcomes and adherence to sepsis management protocols in emergency departments. . Medscape Medical News
Medscape Infectious Diseases
17.06.2024
Delays in antibiotic administration increased the mortality risk by threefold in children with sepsis presenting to the ED. . Medscape Medical News
Medscape Infectious Diseases
4.06.2024
Public reporting of sepsis outcomes, including hospital deaths, isn't telling the whole story. . Medscape