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Dokumenter [5] Sider [2] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [+20]
Dokumenter [5]

Initial diagnostik og behandling af formodet akut bakteriel meningitis.

Udgiver: Dansk Selskab for Infektionsmedicin 2018

Rapport og anbefaling vedrørende ulemper og fordele ved henholdsvis at undlade eller gennemføre lumbalpunktur for patienter i blodfortyndende behandling mistænkt for akut bakteriel meningitis.

Denne vejledning er tiltænkt diagnostik og behandling af formodet Lyme neuroborreliose hos voksne. Vejledningen er udarbejdet som et supplement til Borrelia klaringsrapport (2014).

Af Rikke Krogh-Madsen, formand for Dansk Selskab for Infektionsmedicin. Der er lige nu massivt fokus på læger der har begået fejl. Aktuelt drejer det sig om behandling af meningokoksygdom. Bestyrelsen for Dansk Selskab for Infektionsmedicin (DSI) kender ikke til detaljerne i de konkrete sager og har ikke set sagsakterne. Dette er derfor en generel udtalelse som tager udgangspunkt i udmeldingen fra Patienterstatningen vedr. de tre meningokok-sager.

Sider [2]

…ane Agergaard, Morten Sodemann og Marie Nørredam Influenza: Jens Lundgren (tovholder), Thomas Benfield, Jan Gerstoft, Isik Johansen, Gitte Kronborg, Henrik Nielsen, Lene Surland Knudsen, Merete Storgaard og Ole Kirk Influenza, Meningitis og encephalitis: Christian Brandt (tovholder), Helene Mens, Lars Omland, Lykke Larsen, Jacob Bodilsen, Lothar Wiese, Birgitte Rønde Hansen, Hans Rudolf von Lüttchau, Henrik Nielsen (referent) Akut bakteriel meningitis, Viral meningitis,.

. Sted: Auditorium A, Forskningens Hus, Aalborg Universitets Hospital, Syd, Søndre Skovvej 15, 9000 Aalborg. Program: Torsdag d. 19/9. 09.30-10.00 Kaffe og velkomst. 10.00-10.15 DASGIB og andre nationale samarbejder HN. 10.15-11.00 Viral meningitis. Christian Brandt. 11.00-11.10 PAUSE. 11.10-11.40 Infektiøs encephalitis (del 1). Jacob Bodilsen. 11.40-12.00 Kursister – CASE gruppe 1. 12.00-13.00 FROKOST. 13.00-13.40 Infektiøs encephalitis (del 2). Jacob Bodilsen.

…e Bengaard Andersen kommenterer: Læs ikke denne artikel - med mindre du har særlig tuberkulose interesse. Men hvem har ikke det i vores selskab? 'Linezolid manifests a rapid and dramatic therapeutic effect for patients with life-threatening tuberculous meningitis' af Feng Sun og kolleger publiceret i Antimicrobial Agents and Chemotherapy - et retrospektivt studie fra Kina, der antyder at Linezolid kan give et godt bidrag til behandling af tuberkuløs meningitis.

… Johansen kommenterer: Et trist resultat: I 2013 rapporterede Ruslami et al. (Lancet Infect Dis. 2013 Jan;13(1):27-35) nedsat mortalitet ved IV administrering af en øget dosis Rifampicin og Moxifloxacin i blot 14 dage til ca. 60 patienter med tuberkuløs meningitis - efterfulgt af standard behandling. Der var derfor store forventninger til denne store kliniske trial, hvor effekten af øget Rifampicin dosis samt et flourquinolon (per oralt) blev undersøgt på ca. 700 Vietnamesiske patienter.

…ndgrens studie af, hvornår man kan holde op med at give pneumocyste-profylakse til HIV-smittede eller de Gans studiet, der ændrede fik indført dexamethason i retningslinjerne for purulent meningitis. Her er formentlig et nyt studie, der kommer til at få indflydelse på standardbehandlingen af patienter med svær pneumoni. Læs en gang - og døm selv - jeg tager den med til næste års "Journal Highlights of the year", men tænkte at den måske allerede nu var god at få kendskab til. God læselyst :-)

Nyt fra tidsskrifterne [+20]

Der er mere end 20 resultater, måske du vil se flere resultater her?

Journal of Infectious Diseases
29.04.2025
Abstract . Background . Several ongoing clinical trials are evaluating high-dose rifampicin (up to 35 mg/kg) for tuberculous meningitis (TBM). However, rifampicin pharmacokinetics at higher doses is not fully characterized, particularly in cerebrospinal fluid (CSF), the site of TBM disease.Methods .
Clinical Infectious Diseases
26.04.2025
Abstract . The promising results of the Ambition-CM trial in persons with HIV have sparked interest in treating non-HIV-associated cryptococcal meningitis with single 10mg/kg liposomal amphotericin B, combined with oral flucytosine and fluconazole. However, caution is warranted when applying this approach to non-HIV organ transplant recipients, whose immune status may vary due to the effects of immunosuppressive drugs.
BMC Infectious Diseases
24.04.2025
Bacterial meningitis is a severe infectious disease. Study of bacterial meningitis of children in recent years are limited. It is unclear whether there have been any changes in the epidemiological characteristics of bacterial meningitis during the years of the COVID-19 pandemic. The purpose of this study was to describe a large, nationwide study of bacterial meningitis in China. We analyzed data of hospitalized patients with bacterial meningitis from 30 hospitals in China from 2016—2021.
BMC Infectious Diseases
22.04.2025
. Background. Meningitis during the neonatal period is a potentially devastating condition with high morbidity and mortality. Pathogens cause meningitis varying with gestational age at birth, age at presentation, and geographic location. . Methods.
BMC Infectious Diseases
16.04.2025
. Background. In 2017, WHO published a list of bacteria for which new antibiotics are urgently needed. The main bacteria are common causes of nosocomial meningitis. The key focuses are carbapenem resistance, vancomycin resistance, methicillin resistance, and extended-spectrum beta-lactamase (ESBL) production.
Journal of Infectious Diseases
9.04.2025
Abstract . Tuberculous meningitis (TBM) remains the most lethal form of tuberculosis (TB). Despite significant physiological differences, adults, and children with TBM receive similar treatment and are often grouped together in research. Consequently, differences in TBM characteristics across the lifespan are poorly understood but may be relevant to developing more effective and age-appropriate interventions.
BMC Infectious Diseases
6.04.2025
. Background. Tuberculous meningitis (TBM) is the most severe form of tuberculosis, with high morbidity and mortality. This retrospective study evaluates the clinical efficacy of linezolid in patients with TBM. . Methods. We analyzed 99 TBM patients treated at the Shanghai Public Health Clinical Center from June 2013 to March 2020.
BMJ Open
3.04.2025
. Introduction. Childhood tuberculous meningitis (TBM) is a devastating disease. The long-standing WHO recommendation for treatment is 2 months of intensive phase with isoniazid (H), rifampicin (R), pyrazinamide (Z) and ethambutol (E), followed by 10 months of isoniazid and rifampicin. In 2022, WHO released a conditional recommendation that 6 months of intensified antituberculosis therapy (ATT) could be used as an alternative for drug-susceptible TBM.
American Journal of Tropical Medicine and Hygiene
3.04.2025
. . Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 112 Issue: 4 Pages: 856-858. .
International Journal of Infectious Diseases
2.04.2025
Probiotics, defined as live microorganisms that confer health benefits when administered in adequate quantities [1], have demonstrated efficacy in reducing neonatal complications including necrotizing enterocolitis (NEC), all-cause mortality, late-onset sepsis, and feeding intolerance [2]. Clostridium butyricum (C. butyricum) is a strict anaerobe, producing butyric acid as a metabolic byproduct, hence also called butyric acid bacteria. C.
Clinical Microbiology and Infection
25.03.2025
Pneumococcal meningitis is a severe infection with high mortality and morbidity rates [1]. Despite advances in antimicrobial therapy and supportive care, new treatment strategies are required to improve outcome [1]. One frequently observed complication is an elevated intracranial pressure (ICP), attributed to several pathophysiological mechanisms, including brain swelling due to cerebritis, cerebral infarctions, thrombosis and hemorrhages resulting from blood vessel inflammation [2].
BMC Infectious Diseases
23.03.2025
… Background. In low-resource settings, limited laboratory capacity adds to the burden of central nervous system (CNS) infections in children and spurs overuse of antibiotics. The commercially available BioFire® FilmArray® Meningitis/Encephalitis Panel (FA-ME) with its capability to simultaneously detect 14 pathogens in cerebrospinal fluid (CSF), could potentially narrow such a diagnostic gap. . Methods.
Infection
6.03.2025
. Background. Despite significant advances in prevention and treatment strategies, meningitis continues to pose a substantial global health challenge. The disease burden demonstrates marked geographical disparities, with disproportionate impact in resource-limited settings, particularly within the “meningitis belt” of Sub-Saharan Africa. The global meningitis burden is influenced by a complex interplay of environmental, behavioral, and socioeconomic determinants.
Infection
4.03.2025
. Abstract. . Background. Despite significant advances in prevention and treatment strategies, meningitis continues to pose a substantial global health challenge. The disease burden demonstrates marked geographical disparities, with disproportionate impact in resource-limited settings, particularly within the “meningitis belt” of Sub-Saharan Africa.
Clinical Infectious Diseases
22.02.2025
…m agents with activity against DTR gram-negatives are available including cefiderocol, ceftazidime-avibactam, ceftolozane-tazobactam, imipenem-cilastatin-relebactam, meropenem-vaborbactam, and sulbactam-durlobactam. In this article, we review host and drug factors that influence an antibiotic’s likely effectiveness for the treatment of bacterial meningitis. We also review the preclinical and clinical data in support of or against each of the aforementioned agents for the treatment of bacterial meningitis.
Journal of Infectious Diseases
19.02.2025
Abstract . Background . Tuberculous meningitis (TBM)-related deaths occur early, often within weeks after initiation of treatment. Enhanced treatment early in the disease course with agents that effectively penetrate the central nervous system may improve outcomes in TBM.Methods .
Clinical Microbiology and Infection
14.02.2025
Intracranial devices may be used to treat or guide treatment of increased intracranial pressure in patients with pneumococcal meningitis. European guidelines do not recommend the routine use of intracranial devices in management of pneumococcal meningitis. However, in some countries, intracranial devices are used routinely, but the effect remains unknown.
International Journal of Infectious Diseases
31.01.2025
Human parechovirus (HPeV) infection is increasingly recognized as a cause of severe illness in infants, including sepsis, meningitis, encephalitis, and seizures [1]. In neonates, HPeV encephalitis is associated with white matter injury and neurodevelopmental sequelae [2,3]. To our knowledge, there are only three case reports of congenitally acquired parechovirus infection.
BMC Infectious Diseases
25.01.2025
. Abstract. . Background. Bacterial meningitis (BM) is a life-threatening central nervous system infection with potential for severe neurological sequelae. High mobility group box 1 (HMGB1) is known as a late inflammatory mediator associated with lethal pathology. This study aims to investigate the serial cerebrospinal fluid (CSF) concentrations of HMGB1 in children with BM and its relationship to neurological prognosis. .
Clinical Infectious Diseases
15.01.2025
Abstract . Background . More than half of people diagnosed with human immunodeficiency virus–associated cryptococcal meningitis are antiretroviral therapy (ART)-experienced. The impact of recent ART initiation (≤14 days) on outcomes from cryptococcal meningitis, and how to optimally manage ART in this patient population, are unknown.Methods .
Aktuelle smitsomme sygdomme [+20]

Der er mere end 20 resultater, måske du vil se flere resultater her?

Medscape Infectious Diseases
18.04.2025
The panel was due to vote on influenza vaccine recommendations but delayed that to its June meeting. . Medscape Medical News
ProMED
15.04.2025
. . . MENINGITIS, MENINGOCOCCAL - NIGERIA (05): UPDATE. ************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 10 Apr 2025 . Source: Leadership [edited] . leadership.ng/outbreak-of-meningitis-2/ . . . The country is witnessing a resurgence in the outbreak of infectious.
ProMED
15.04.2025
. . . MENINGOCOCCAL DISEASE - VIET NAM (04): (HANOI) MENINGITIS. *********************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Sun 13 Apr 2025 . Source: VN Express [in Vietnamese, machine trans., edited] . vnexpress.net/ha-noi-ghi-nhan-ca-nao-mo-cau-dau-tien-trong-nam-4873478.html . . .
ProMED
9.04.2025
. . . MENINGITIS, MENINGOCOCCAL - NIGERIA (04): UPDATE. ************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Mon 7 Apr 2025 . Source: Premium Times [edited] . www.premiumtimesng.com/health/786312-meningitis-kebbi-sokoto-lead-as-nigeria-records-1858-suspected-cases.html . . .
ProMED
29.03.2025
. . . MENINGITIS, MENINGOCOCCAL - NIGERIA (03): FATAL. ***********************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 27 Mar 2025 . Source: Punch [edited] . punchng.com/meningitis-kebbi-katsina-lead-as-ncdc-records-807-suspected-cases-74-deaths/ . . . The Nigeria Centre for Disease Control and Prevention (NCDC) said the.
Medscape Infectious Diseases
27.03.2025
Children with pneumococcal meningitis have a lower risk for 30-day mortality when treated with early adjunctive dexamethasone, a study shows. . Medscape News UK
ProMED
25.03.2025
. . . MENINGITIS, MENINGOCOCCAL - NIGERIA (02): (KEBBI) FATAL. *******************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Wed 19 Mar 2025 . Source: Daily Trust [edited] . dailytrust.com/meningitis-death-toll-rises-to-55-in-kebbi/ . . . The Kebbi State Government says the death toll in the outbreak of.
ProMED
16.03.2025
. . . MENINGITIS, VIRAL - INDIA: (KERALA). ***********************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 13 Mar 2025 . Source: TimesNow [edited] . www.timesnownews.com/health/meningitis-cases-surge-in-kochi-2-kids-infected-3-show-symptoms-is-your-child-at-risk-article-118960219 . . . Five students from St.
ProMED
15.03.2025
. . . MENINGITIS - GHANA (04): (UPPER WEST, UPPER EAST) UPDATE, ALERT. ***************************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Mon 10 Mar 2025 15:01 GMT . Source: 3 News [edited] . 3news.com/news/ghs-on-high-alert-for-severer-strain-of-meningitis-director-general/ . . .
ProMED
14.03.2025
. . . MENINGITIS, MENINGOCOCCAL - NIGERIA: (KEBBI) FATAL. **************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Tue 11 Mar 2025 . Source: Newsday.com [edited] . www.newsday.com/news/nation/nigeria-meningitis-outbreak-kebbi-m92852 . . . Nigerian authorities confirmed Tuesday [11 Mar 2025] that a meningitis.
ProMED
3.03.2025
. . . MENINGITIS - GHANA (03): (UPPER WEST) UPDATE. ********************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Tue 25 Feb 2025 . Source: Citi Newsroom [edited] . citinewsroom.com/2025/02/csm-outbreak-in-upper-west-region-worsens-173-cases-16-deaths/ . . . The Upper West Region is grappling with a worsening meningitis.
ProMED
28.02.2025
. . . MENINGITIS - TUNISIA: (KAIROUAN) UNIVERSITY STUDENTS, FATAL, REQUEST. FOR INFORMATION. ************************************************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Mon 24 Feb 2025 . Source: AlArarby Algadid [in Arabic, trans. & summ. Mod.MM, edited] . tinyurl.com/kanuk898 . . .
ProMED
26.02.2025
. . . MENINGOCOCCAL DISEASE - VIET NAM (02): (HO CHI MINH CITY) MENINGITIS. ********************************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Mon 24 Feb 2025 . Source: VN Express [in Vietnamese, machine trans., edited] . vnexpress.net/nguoi-dan-ong-o-tp-hcm-mac-nao-mo-cau-4853017.html . . .
ProMED
11.02.2025
. . . MENINGITIS - GHANA (02): (UPPER WEST) UPDATE. ********************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 7 Jan 2025 . Source: MSN/Ghana News Agency [edited] . tinyurl.com/367jekcn . . . Dr Sebastian Ngmenenso Sandaare, a National Democratic Congress (NDC). Member of Parliament (MP) for Daffiama Bussie Issa, has sounded the.
ProMED
6.02.2025
. . . MENINGITIS, MENINGOCOCCAL - TAIWAN: FIRST CASE OF THE YEAR, ELDERLY,. FATAL. **************************************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Wed 5 Feb 2025 . Source: Focus Taiwan [edited] . focustaiwan.tw/society/202502050005 . . . Taiwan has reported its 1st case of meningococcal meningitis this year.
ProMED
2.02.2025
. . . MENINGITIS - GHANA: (UPPER WEST) FATAL. **************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Mon 27 Jan 2025 . Source: Citi Newsroom [edited] . citinewsroom.com/2025/01/upper-west-region-records-17-suspected-cases-of-meningitis-6-deaths/ . . . The Upper West Region has reported 17 suspected cases of cerebrospinal.
ProMED
20.01.2025
. . . MENINGITIS - TOGO: (KARA) EPIDEMIC. **********************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Wed 15 Jan 2025 . Source: Togo Scoop Info [in French, machine trans., edited] . togoscoop.tg/epidemie-de-meningite-le-district-de-dankpen-en-alerte/ . . . A series of meningitis cases have been reported in the Kara region,.
Medscape Infectious Diseases
14.05.2024
Meningitis was among three strong clinical risk factors identified in a nationwide, population-based study. . Medscape Medical News
ProMED
17.04.2025
…n under 5 years old. . The main manifestation is skin and mucosal lesions in the form of. blisters in special locations such as the oral mucosa, palms, soles,. buttocks, and knees. The disease can cause many dangerous. complications such as encephalitis, meningitis, myocarditis, and acute. pulmonary edema leading to death if not detected early and treated. promptly. . Doctors advise families not to worry too much when their children show. signs of hand-foot-mouth disease, but also not to be subjective.
ProMED
16.04.2025
…. gram-positive bacterial strains that represents a primary health. problem in the swine industry worldwide. _S. suis_ is also an emerging. zoonotic pathogen that causes severe human infections clinically. featuring with varied diseases/syndromes (such as meningitis,. septicemia, and arthritis). Over the past few decades, continued. efforts have made significant progress toward better understanding. this zoonotic infectious entity, contributing in part to the.

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