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Anorectal lymphogranuloma venereum among men who have sex with men: a 3-year nationwide survey, France, 2020 to 2022
Olivia Peuchant, Cécile Laurier-Nadalié, Laura Albucher, Carla Balcon, Amandine Dolzy, Nadège Hénin, Arabella Touati, Cécile Bébéar and on behalf of the Anachla study group
Eurosurveillance latest updates, 10.05.2024
Tilføjet 10.05.2024
BackgroundIn France, lymphogranuloma venereum (LGV) testing switched from universal to selective testing in 2016. AimTo investigate changes in LGV-affected populations, we performed a nationwide survey based on temporarily reinstated universal LGV testing from 2020 to 2022. MethodsEach year, during three consecutive months, laboratories voluntarily sent anorectal Chlamydia trachomatis-positive samples from men and women to the National Reference Centre for bacterial sexually transmitted infections. We collected patients’ demographic, clinical and biological data. Genovars L of C. trachomatis were detected using real-time PCR. In LGV-positive samples, the ompA gene was sequenced. ResultsIn 2020, LGV positivity was 12.7% (146/1,147), 15.2% (138/907) in 2021 and 13.3% (151/1,137) in 2022 (p > 0.05). It occurred predominantly in men who have sex with men (MSM), with rare cases among transgender women. The proportion of HIV-negative individuals was higher than that of those living with HIV. Asymptomatic rectal LGV increased from 36.1% (44/122) in 2020 to 52.4% (66/126) in 2022 (p = 0.03). Among users of pre-exposure prophylaxis (PrEP), LGV positivity was 13.8% (49/354) in 2020, 15.6% (38/244) in 2021 and 10.9% (36/331) in 2022, and up to 50% reported no anorectal symptoms. Diversity of the LGV ompA genotypes in the Paris region increased during the survey period. An unexpectedly high number of ompA genotype L1 variant was reported in 2022. ConclusionIn rectal samples from MSM in France, LGV positivity was stable, but the proportion of asymptomatic cases increased in 2022. This underscores the need of universal LGV testing and the importance of continuous surveillance.
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New HIV Infections After Vampire Facials at Unlicensed Spa
Medscape Infectious Diseases, 3.05.2024
Tilføjet 3.05.2024
The cosmetic procedures took place at a spa performing microneedling facials using unsterile injection practices. Medscape Medical News
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New Contraindications to Coadministration of Atazanavir
Medscape Infectious Diseases, 26.04.2024
Tilføjet 26.04.2024
New restrictions have been imposed by the European Medicines Agency on the coadministration of the anti-HIV drug atazanavir with a variety of other agents. Medscape Medical News
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MASLD Plus HIV Ups Risk for CVD But Not Liver Disease
Medscape Infectious Diseases, 26.04.2024
Tilføjet 26.04.2024
A large study reveals an increased risk for adverse cardiovascular events but not for liver disease progression in adults with MASLD disease and HIV infection. Medscape Medical News
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Investigation of Presumptive HIV Transmission Associated with Receipt of Platelet-Rich Plasma Microneedling Facials at a Spa Among Former Spa Clients - New Mexico, 2018-2023
Morbidity and Mortality Weekly Report (MMWR), 26.04.2024
Tilføjet 26.04.2024
This report describes an investigation of multiple HIV infections among people who received microneedling facials.
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