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8 emner vises.
1
How the New MRSA Antibiotic Cracked Open AI's 'Black Box'
Medscape Infectious Diseases, 13.02.2024
Tilføjet 13.02.2024
Researchers who uncovered a fresh class of antibiotics used a new process — explainable AI — that could propel drug discovery. Medscape Medical News
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2
Clinical epidemiology and case fatality due to antimicrobial resistance in Germany: a systematic review and meta-analysis, 1 January 2010 to 31 December 2021
Maria Rödenbeck, Olaniyi Ayobami, Tim Eckmanns, Mathias W Pletz, Jutta Bleidorn and Robby Markwart
Eurosurveillance latest updates, 19.05.2023
Tilføjet 19.05.2023
BackgroundAntimicrobial resistance (AMR) is of public health concern worldwide. AimWe aimed to summarise the German AMR situation for clinicians and microbiologists. MethodsWe conducted a systematic review and meta-analysis of 60 published studies and data from the German Antibiotic-Resistance-Surveillance (ARS). Primary outcomes were AMR proportions in bacterial isolates from infected patients in Germany (2016–2021) and the case fatality rates (2010–2021). Random and fixed (common) effect models were used to calculate pooled proportions and pooled case fatality odds ratios, respectively. ResultsThe pooled proportion of meticillin resistance in Staphylococcus aureus infections (MRSA) was 7.9% with a declining trend between 2014 and 2020 (odds ratio (OR) = 0.89; 95% CI: 0.886–0.891; p
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3
Opgørelse over blodforgiftning med MRSA i 4. kvartal 2020
Statens Serum Institut, 11.04.2023
Tilføjet 11.04.2023
Referencelaboratoriet for Antibiotikaresistens på Statens Serum Institut opgør hvert kvartal antallet af blodforgiftninger forårsaget af MRSA samt dødsfald som følge af disse.
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4
Opgørelse for blodforgiftning med MRSA 1. kvartal 2019
Statens Serum Institut, 11.04.2023
Tilføjet 11.04.2023
Referencelaboratoriet for Antibiotikaresistens på Statens Serum Institut opgør hvert kvartal antallet af blodforgiftninger forårsaget af MRSA samt dødsfald som følge af disse.
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5
Flere multiresistente bakterier på danske hospitaler
Statens Serum Institut, 11.04.2023
Tilføjet 11.04.2023
Der var i 2013 en stor stigning i antallet af patienter, der fik infektioner med multiresistente bakterier som VRE og CPE på de danske hospitaler. Derimod fastholdtes antallet af hospitals MRSA infektioner på samme lave niveau som året før. Det viser årets DANMAP rapport fra Statens Serum Institut og DTU Fødevareinstituttet.
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6
12 nye tilfælde af blodforgiftninger på grund af antibiotikaresistente stafylokokker (MRSA)
Statens Serum Institut, 16.02.2023
Tilføjet 16.02.2023
I 4. kvartal 2022 blev der registreret 12 nye tilfælde af blodforgiftning med MRSA. Tre af patienterne døde. Det viser den seneste opgørelse fra Statens Serum Institut.
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7
Molecular surveillance of multidrug-resistant Gram-negative bacteria in Ukrainian patients, Germany, March to June 2022
Eurosurveillance latest updates, 5.01.2023
Tilføjet 6.01.2023
BackgroundSince the beginning of the war in Ukraine in February 2022, Ukrainians have been seeking shelter in other European countries.AimWe aimed to investigate the prevalence and the molecular epidemiology of multidrug-resistant Gram-negative (MDRGN) bacteria and meticillin-resistant Staphylococcus aureus (MRSA) in Ukrainian patients at admittance to the University Hospital Frankfurt, Germany.MethodsWe performed screening and observational analysis of all patients from March until June 2022. Genomes of MDRGN isolates were analysed for antimicrobial resistance, virulence genes and phylogenetic relatedness.ResultsWe included 103 patients (median age: 39 ± 23.7 years), 57 of whom were female (55.3%; 95% confidence interval (CI): 45.2–5.1). Patients were most frequently admitted to the Department of Paediatrics (29/103; 28.2%; 95% CI: 19.7–37.9). We found 34 MDRGN isolates in 17 of 103 patients (16.5%; 95% CI: 9.9–25.1). Ten patients carried 21 carbapenem-resistant (CR) bacteria, five of them more than one CR isolate. Four of six patients with war-related injuries carried eight CR isolates. In six of 10 patients, CR isolates caused infections. Genomic characterisation revealed that the CR isolates harboured at least one carbapenemase gene, blaNDM-1 being the most frequent (n = 10). Core genome and plasmid analysis revealed no epidemiological connection between most of these isolates. Hypervirulence marker genes were found in five of six Klebsiella pneumoniae CR isolates. No MRSA was found.ConclusionHospitals should consider infection control strategies to cover the elevated prevalence of MDRGN bacteria in Ukrainian patients with war-related injuries and/or hospital pre-treatment and to prevent the spread of hypervirulent CR isolates.
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8
18 nye tilfælde af blodforgiftninger på grund af antibiotikaresistente stafylokokker (MRSA)
Statens Serum Institut, 17.12.2022
Tilføjet 17.12.2022
I 3. kvartal 2022 blev der registreret 18 nye tilfælde af blodforgiftning med MRSA. Tre af patienterne døde. Det viser den seneste opgørelse fra Statens Serum Institut.
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