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6 ud af 6 tidsskrifter valgt, søgeord (pneumoni) valgt, emner højest 180 dage gamle, sorteret efter nyeste først. Opdateret for 8 dage siden.51 emner vises.
Each of the 828 opioid and 2,737 systemic steroid prescriptions in the data set represent a potentially inappropriate prescription.
Isabelle Vock, Lisandra Aguilar-Bultet, Adrian Egli, Pranita D Tamma and Sarah Tschudin-Sutter
Algorithms for predicting infection with extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE) on hospital admission or in patients with bacteraemia have been proposed, aiming to optimise empiric treatment decisions.
We sought to confirm external validity and transferability of two published prediction models as well as their integral components.
We performed a retrospective case–control study at University Hospital Basel, Switzerland. Consecutive patients with ESBL-producing Escherichia coli or Klebsiella pneumoniae isolated from blood samples between 1 January 2010 and 31 December 2016 were included. For each case, three non-ESBL-producing controls matching for date of detection and bacterial species were identified. The main outcome measure was the ability to accurately predict infection with ESBL-PE by measures of discrimination and calibration.
Overall, 376 patients (94 patients, 282 controls) were analysed. Performance measures for prediction of ESBL-PE infection of both prediction models indicate adequate measures of calibration, but poor discrimination (area under receiver-operating curve: 0.627 and 0.651). History of ESBL-PE colonisation or infection was the single most predictive independent risk factor for ESBL-PE infection with high specificity (97%), low sensitivity (34%) and balanced positive and negative predictive values (80% and 82%).
Applying published prediction models to institutions these were not derived from, may result in substantial misclassification of patients considered as being at risk, potentially leading to wrong allocation of antibiotic treatment, negatively affecting patient outcomes and overall resistance rates in the long term. Future prediction models need to address differences in local epidemiology by allowing for customisation according to different settings.
Nadia Oreshkova, Robert Jan Molenaar, Sandra Vreman, Frank Harders, Bas B Oude Munnink, Renate W Hakze-van der Honing, Nora Gerhards, Paulien Tolsma, Ruth Bouwstra, Reina S Sikkema, Mirriam GJ Tacken, Myrna MT de Rooij, Eefke Weesendorp, Marc Y Engelsma, Christianne JM Bruschke, Lidwien AM Smit, Marion Koopmans, Wim HM van der Poel and Arjan Stegeman
Respiratory disease and increased mortality occurred in minks on two farms in the Netherlands, with interstitial pneumonia and SARS-CoV-2 RNA in organ and swab samples. On both farms, at least one worker had coronavirus disease-associated symptoms before the outbreak. Variations in mink-derived viral genomes showed between-mink transmission and no infection link between the farms. Inhalable dust contained viral RNA, indicating possible exposure of workers. One worker is assumed to have attracted the virus from mink.
Hospital-Related Infection -- Australia1. Casolari C, Pecorari M, Fabio G, et al.: A simultaneous outbreak of _Serratia marcescens_ and _Klebsiella pneumoniae_ in a neonatal intensive care unit. J Hosp Infect. 2005; 61(4): 312-20. doi: 10.1016/j.jhin.2005.03.005; abstract available at .2. van Ogtrop ML, van Zoeren-Grobben D, Verbakel-Salomons EM, van Boven CP: _Serratia marcescens_ infections in neonatal departments: description of an outbreak and review of the literature. J Hosp Infect. 1997; 36(2): 95-103; abstract available at
For tredje år i træk er der blevet anmeldt et højt antal tilfælde af legionella-pneumoni til Statens Institut.
Melioidosis -- United StatesOn 17 Nov 2018, a 63-year-old man from Atascosa County, Texas, came to hospital A with fever, chest pain, and dyspnea of 3 days' duration. At admission, he reported congenital unilateral renal agenesis. Renal function measures were unremarkable. Increased hemoglobin A1c level and hyperglycemia (glucose over 200 mg/dL) suggested undiagnosed type 2 diabetes.Computed tomography of chest and abdomen with intravenous contrast showed left lower lobe pneumonia with a small left pleural effusion.
Catherine Ludden, Felix Lötsch, Erik Alm, Narender Kumar, Karin Johansson, Barbara Albiger, Te-Din Huang, Olivier Denis, Anette M Hammerum, Henrik Hasman, Jari Jalava, Kati Räisänen, Laurent Dortet, Agnès B Jousset, Sören Gatermann, Sebastian Haller, Martin Cormican, Wendy Brennan, Maria Del Grosso, Monica Monaco, Leo Schouls, Ørjan Samuelsen, Mateja Pirš, Tjaša Cerar, Jésus Oteo-Iglesias, Maria Pérez-Vázquez, Karin Sjöström, Petra Edquist, Katie L Hopkins, Marc J Struelens, Daniel Palm, Dominique L Monnet
Analysis of sequencing data for 143 blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae isolates from 13 European national collections and the public domain resulted in the identification of 15 previously undetected multi-country transmission clusters. For 10 clusters, cases had prior travel/hospitalisation history in countries outside of the European Union including Egypt, Iran, Morocco, Russia, Serbia, Tunisia and Turkey. These findings highlight the benefit of European whole genome sequencing-based surveillance and data sharing for control of antimicrobial resistance.
Yinong Young-Xu, Julia Thornton Snider, Salaheddin M Mahmud, Ellyn M Russo, Robertus Van Aalst, Edward W Thommes, Jason KH Lee and Ayman Chit
It is unclear whether high-dose influenza vaccine (HD) is more effective at reducing mortality among seniors.
This study aimed to evaluate the relative vaccine effectiveness (rVE) of HD.
We linked electronic medical record databases in the Veterans Health Administration (VHA) and Medicare administrative files to examine the rVE of HD vs standard-dose influenza vaccines (SD) in preventing influenza/pneumonia-associated and cardiorespiratory mortality among VHA-enrolled veterans 65 years or older during the 2012/13, 2013/14 and 2014/15 influenza seasons. A multivariable Cox proportional hazards model was performed on matched recipients of HD vs SD, based on vaccination time, location, age, sex, ethnicity and VHA priority level.
Among 569,552 person-seasons of observation, 207,574 (36%) were HD recipients and 361,978 (64%) were SD recipients, predominantly male (99%) and white (82%). Pooling findings from all three seasons, the adjusted rVE estimate of HD vs SD during the high influenza periods was 42% (95% confidence interval (CI): 24–59) against influenza/pneumonia-associated mortality and 27% (95% CI: 23–32) against cardiorespiratory mortality. Residual confounding was evident in both early and late influenza periods despite matching and multivariable adjustment. Excluding individuals with high 1-year predicted mortality at baseline reduced the residual confounding and yielded rVE of 36% (95% CI: 10–62) and 25% (95% CI: 12–38) against influenza/pneumonia-associated and cardiorespiratory mortality, respectively. These were confirmed by results from two-stage residual inclusion estimations.
The HD was associated with a lower risk of influenza/pneumonia-associated and cardiorespiratory death in men during the high influenza period.
Other Animal Disease -- United StatesWith about 400 animals, Oregon's Lookout Mountain bighorn sheep herd is considered to be one of the biggest in the state. However, recent reports of bighorns coughing have state wildlife biologists concerned the disease -- particularly pneumonia -- could impact the future of the herd. The Oregon Department of Fish and Wildlife (ODFW) are closely monitoring the herd to see what happens but won't know "how severe the death toll" will be until later this year , The Bulletin reports
Jessica Ohland, Charlotte Warren-Gash, Ruth Blackburn, Kåre Mølbak, Palle Valentiner-Branth, Jens Nielsen and Hanne-Dorthe Emborg
Several studies have investigated a possible association between respiratory infection and acute myocardial infarction (MI). As both influenza and pneumococcal infections are vaccine preventable, understanding the populations affected by virus-induced cardiovascular complications is important to guide public health and clinical practice.
This observational study aimed to quantify the association between laboratory-confirmed respiratory bacteria or virus infections and risk of first MI or stroke, by using self-controlled case series (SCCS) analysis of anonymised linked electronic Danish health records.
The SCCS method was used to determine the relative incidence of the first event of MI and stroke occurring within 28 days after laboratory-confirmed respiratory infections compared with the baseline time period.
In the age and season adjusted analyses for first acute MI, the incidence ratios (IR) of a MI event occurring during the risk period were significantly elevated following a Streptococcus pneumoniae infection with values of 20.1, 11.0 and 4.9 during 1–3, 4–7 and 8–14 days, respectively and following respiratory virus infection with values of 15.2, 4.5 and 4.4 during 1–3, 8–14 and 15–28 days, respectively. The significantly elevated IRs for stroke following an S. pneumoniae infection were 25.5 and 6.3 during 1–3 and 8–14 days, respectively and following respiratory virus infection 8.3, 7.8 and 6.2 during 1–3, 4–7 and 8–14 days, respectively.
This study suggested a significant cardiovascular event triggering effect following infection with S. pneumoniae and respiratory viruses (mainly influenza), indicating the importance of protection against vaccine-preventable respiratory infections.
Information about chest imaging findings in children with COVID-19 pneumonia is scarce, but a new consensus statement sheds light on use and interpretation.
Meng Lv, Xufei Luo, Janne Estill, Yunlan Liu, Mengjuan Ren, Jianjian Wang, Qi Wang, Siya Zhao, Xiaohui Wang, Shu Yang, Xixi Feng, Weiguo Li, Enmei Liu, Xianzhuo Zhang, Ling Wang, Qi Zhou, Wenbo Meng, Xiaolong Qi, Yangqin Xun, Xuan Yu, Yaolong Chen and on behalf of the COVID-19 evidence and recommendations working group
In December 2019, a pneumonia caused by a novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and has rapidly spread around the world since then.
This study aims to understand the research gaps related to COVID-19 and propose recommendations for future research.
We undertook a scoping review of COVID-19, comprehensively searching databases and other sources to identify literature on COVID-19 between 1 December 2019 and 6 February 2020. We analysed the sources, publication date, type and topic of the retrieved articles/studies.
We included 249 articles in this scoping review. More than half (59.0%) were conducted in China. Guidance/guidelines and consensuses statements (n = 56; 22.5%) were the most common. Most (n = 192; 77.1%) articles were published in peer-reviewed journals, 35 (14.1%) on preprint servers and 22 (8.8%) posted online. Ten genetic studies (4.0%) focused on the origin of SARS-CoV-2 while the topics of molecular studies varied. Nine of 22 epidemiological studies focused on estimating the basic reproduction number of COVID-19 infection (R0). Of all identified guidance/guidelines (n = 35), only ten fulfilled the strict principles of evidence-based practice. The number of articles published per day increased rapidly until the end of January.
The number of articles on COVID-19 steadily increased before 6 February 2020. However, they lack diversity and are almost non-existent in some study fields, such as clinical research. The findings suggest that evidence for the development of clinical practice guidelines and public health policies will be improved when more results from clinical research becomes available.
A 62-year-old dermatologist shared his story of being treated for COVID-19-associated pneumonia while still on oxygen in the hospital.
Plague -- UgandaPlague, an acute zoonosis caused by _Yersinia pestis_, is endemic in the West Nile region of northwestern Uganda and neighboring northeastern Democratic Republic of the Congo (DRC) (1-4). The illness manifests in multiple clinical forms, including bubonic and pneumonic plague. Pneumonic plague is rare, rapidly fatal, and transmissible from person to person via respiratory droplets. On 4 Mar 2019, a patient with suspected pneumonic plague was hospitalized in West Nile, Uganda, 4 days after
Pneumonia -- FranceCassir N, Pascal L, Ferrieux D, Bruel C, et al.Abstract----------We report the 3rd outbreak of pneumococcal pneumonia within one year among workers in European shipyards. During January and February 2020, 37 cases of pneumonia were identified in a shipyard in Marseille, southeastern France. Outbreak control measures were implemented, including a mass vaccination campaign with 23-valent pneumococcal polysaccharide vaccine targeting all shipyard workers. Given the high mobility of
Nadim Cassir, Laurence Pascal, David Ferrieux, Christiane Bruel, Christophe Guervilly, Stanislas Rebaudet, Kostas Danis, Lora Kopec, Florence Fenollar, Emmanuelle Varon, Véronique Vig, Jean-Luc Lasalle, Lauriane Ramalli, Pierre Michelet, Jean-Christophe Lagier, Nicolas Persico, Philippe Brouqui, Philippe Malfait and Philippe Parola
We report the third outbreak of pneumococcal pneumonia within one year among workers in European shipyards. During January and February 2020, 37 cases of pneumonia were identified in a shipyard in Marseille, south-eastern France. Outbreak control measures were implemented, including a mass vaccination campaign with 23-valent pneumococcal polysaccharide vaccine targeting all shipyard workers. Given the high mobility of shipyard workers, coordinated responses between European public health institutes are necessary to avoid further outbreaks.
Kristin Tolksdorf, Silke Buda, Ekkehard Schuler, Lothar H Wieler and Walter Haas
Information on severity of coronavirus disease (COVID-19) (transmissibility, disease seriousness, impact) is crucial for preparation of healthcare sectors. We present a simple approach to assess disease seriousness, creating a reference cohort of pneumonia patients from sentinel hospitals. First comparisons exposed a higher rate of COVID-19 patients requiring ventilation. There were more case fatalities among COVID-19 patients without comorbidities than in the reference cohort. Hospitals should prepare for high utilisation of ventilation and intensive care resources.
Maricopa County Department of Public Health in Arizona investigated a cluster of two genetically similar antibiotic-resistant bacterial infections in residents of the ventilator-capable unit of a skilled nursing facility to look for health care-associated bacterial spread.
Klebsiella pneumoniae, Tuberculosis, Other Human Disease, HIV/AIDS, Yellow Fever, Hepatitis, E. coli, Dengue, Trichinosis, Gastroenteritis, Staph, Hepatitis B, Pasteurellosis, Zika virus, Chikungunya, Hepatitis C, Pneumonia, Lassa Fever, Meningitis - Neisseria, Mycobacteria, non-TB, Taeniasis, Q Fever -- NepalGeographical variability in anticapsular IgG levels elicited by pneumococcal conjugate vaccines: Implications for clinical protection?Int J Infect Dis. 2020; 92(Mar): 259-260.William P
Rapid identification of a suspected case of pneumonic plague in the remote West Nile region of Uganda and the timely response by well-trained Ugandan health officials in the form of contact tracing, antibiotic prophylaxis, and community education prevented any additional cases of plague from occurring.
Plague -- DR CongoOn 22 Feb 2020, the Aungba Health Zone chief medical doctor was alerted that suspect bubonic plague cases were reported in the Ugunzu-Makangi village of the Aterlembe health area, Djugu territory, Ituri Province, DR Congo. Murine epizootics were also mentioned in the Makangi village. On 23 Feb 2020, the chief medical doctor of the Aungba health Zone (Lat 2 33' 00'' Long 30 30' 00'') was appointed to visit the health center of Aterlembe for 2 days to investigate suspect bubonic plague cases.
Plague -- DR Congo
COVID-19 -- China1. Yu Wen-Bin, Tang Guang-da, Zhang Li, Corlett R. (2020). Decoding evolution and transmissions of novel pneumonia coronavirus (SARS-CoV-2) using the whole genomic data.2020. doi 10.12074/202002.00033. .- Mod.ASHealthMap/ProMED-mail map of China: ][See Also:COVID-19 update (11): animal reservoir, intermediate hosts, pangolin susp. http://promedmail.org/post/20200220.7009213COVID-19 update (08): companion animals, RFI http://promedmail.org/post/20200218.7002276COVID-19 update (06):
Morana Tomljenovic, Mato Lakic, Tatjana Vilibic-Cavlek, Sanja Kurecic Filipovic, Vesna Visekruna Vucina, Andrea Babic-Erceg, Miljenko Ljubic, Iva Pem Novosel, Maja Ilic, Irena Tabain, Jelena Ivancic-Jelecki, Lisa Hansen and Bernard Kaic
In May 2018, measles was introduced in the Dubrovnik region by an adult who recently travelled to Kosovo*. Control measures and an outbreak investigation were implemented: 15 epidemiologically-linked cases met the outbreak case definition of a visitor/resident of Dubrovnik-Neretva County with laboratory-confirmed measles and symptom onset beginning on May 19. New cases were identified through hospitals and primary care physicians. Throat swabs, urine and/or serum samples were collected from outbreak cases. RT-PCR detection of viral RNA and IgM/IgG was used to confirm infection. The median age of cases was 33 years, with one 8 month-old infant. Vaccination status was unknown for 9 cases, three were unvaccinated, one case had history of one dose and two cases reported receiving two doses of measles-containing vaccine. There were 11 hospitalisations and one person developed pneumonia. Control teams undertook an extensive search of contacts and implemented a range of control measures. Despite the outbreak occurring at the beginning of the summer tourism season, it was contained and did not spread to neighbouring regions. With continuing measles transmission in Europe, even small outbreaks create a burden on the health system in countries which have eliminated measles, and illustrate the importance of maintaining high immunisation coverage.
Pneumonia -- AfghanistanAt least 35 people including women and children have died in the past few weeks due to pneumonia outbreak in Badakhshan Province in the northwestern mountainous area, the provincial health department confirmed.Dr Noor Khawari, head of the provincial public health department, said [Sat 15 Feb 2020] that the people had died in the Wakhan district, a remote area surrounded by high and impassable mountains.He said that 15 of the dead were children, calling malnutrition and cold weather as
Lara Tavoschi, Silvia Forni, Andrea Porretta, Lorenzo Righi, Filippo Pieralli, Francesco Menichetti, Marco Falcone, Giulia Gemignani, Spartaco Sani, Paola Vivani, Tommaso Bellandi, Danilo Tacconi, Lucia Turini, Giulio Toccafondi, Gaetano Privitera, Pierluigi Lopalco, Angelo Baggiani, Fabrizio Gemmi, Grazia Luchini, Maurizio Petrillo, Lorenzo Roti, Patrizio Pezzotti, Annalisa Pantosti, Stefania Iannazzo, Maria Teresa Mechi, Gian Maria Rossolini and on behalf of the Tuscan Clinical Microbiology Laboratory Net
In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.
In December of 2018, Wyoming identified the state's first case of carbapenem-resistant Enterobacteriaceae (CRE) containing mcr-1, which is a gene that can make bacteria resistant to colistin, a drug that can be the last resort for some multidrug-resistant infections like CRE.
Coronavirus -- ChinaChina's ability to control a rapidly spreading coronavirus epidemic is under further strain amid fears that a key test used to confirm new cases is failing to catch large numbers of people with the disease. Problems with so-called nucleic acid tests (NATs) widely used to identify the presence of the previously unknown pneumonia-causing virus make it likely that many infections are going uncounted even as the number of confirmed cases continues to spiral.Authorities are still struggling to
Ine Wouters, Stefanie Desmet, Liesbet Van Heirstraeten, Sereina A Herzog, Philippe Beutels, Jan Verhaegen, Herman Goossens, Pierre Van Damme, Surbhi Malhotra-Kumar, Heidi Theeten and NPcarriage Study Group
The current carriage study was set up to reinforce surveillance during/after the PCV13-to-PCVC10 switch in Belgium.
This observational study monitored carriage of Streptococcus pneumoniae (Sp) serotypes, particularly those no longer covered (3, 6A, 19A), as well as Haemophilus influenzae (Hi), because PCV10 contains the non-typeable Hi protein D.
A total of 2,615 nasopharyngeal swabs from children (6–30 months old) attending day care were collected in three periods over 2016–2018. Children’s demographic and clinical characteristics and vaccination status were obtained through a questionnaire. Sp and Hi were identified by culture and PCR. Pneumococcal strains were tested for antimicrobial (non-)susceptibility by disc diffusion and serotyped by Quellung-reaction (Quellung-reaction and PCR for serotypes 3, 6A, 19A).
The carriage prevalence of Sp (> 75%) remained stable over the successive periods but that of Hi increased (87.4%, 664 Hi-carriers/760 in 2016 vs 93.9%, 895/953 in 2017–2018). The proportion of non-PCV13 vaccine serotypes decreased (94.6%, 438 isolates/463 in 2016 vs 89.7%, 599/668 in 2017–2018) while that of PCV13-non-PCV10 vaccine serotypes (3 + 6A + 19A) increased (0.9%, 4 isolates/463 in 2016 vs 7.8%, 52/668 in 2017–2018), with serotype 19A most frequently identified (87.9%, 58/66 isolates). Non-susceptibility of pneumococci against any of the tested antibiotics was stable over the study period (> 44%).
During and after the PCV13-to-PCV10 vaccine switch, the proportion of non-PCV13 serotypes decreased, mainly due to a serotype 19A carriage prevalence increase. These results complement invasive pneumococcal disease surveillance data, providing further basis for pneumococcal vaccination programme policy making.
Jantien A Backer, Don Klinkenberg and Jacco Wallinga
A novel coronavirus (2019-nCoV) is causing an outbreak of viral pneumonia that started in Wuhan, China. Using the travel history and symptom onset of 88 confirmed cases that were detected outside Wuhan in the early outbreak phase, we estimate the mean incubation period to be 6.4 days (95% credible interval: 5.6–7.7), ranging from 2.1 to 11.1 days (2.5th to 97.5th percentile). These values should help inform 2019-nCoV case definitions and appropriate quarantine durations.
Coronavirus, Polio, Meningitis, Pneumonia, Tuberculosis, Dengue, Other Human Disease, Typhus, Hepatitis B, Chikungunya, Zika virus, Mumps, Measles, Rubella, Yellow Fever, West Nile Virus, Cytomegalovirus, HIV/AIDS, Malaria, Chagas, Avian Influenza, Legionnaires', Whooping Cough, Hepatitis E, Tick-borne Encephalitis, Hepatitis C -- ChinaThe continuing 2019-nCoV epidemic threat of novel coronaviruses to global health: the latest 2019 novel coronavirus outbreak in Wuhan, China.David S Hui, Esam I Azhar, Tariq A Madani, Francine Ntoumi, Richard Kock, Osman Dar, et al.Int J Infect Dis. 2020; 91(Feb): 264-266.Extra time and penalties in the polio endgame.Melinda Suchard, Oyewale Tomori, Lucille BlumbergInt J Infect Dis. 2020; 91(Feb): 252-254.Original reportsBacterial
Coronavirus -- Worldwide/UnknownProf Joseph T Wu, PhD, Kathy Leung, PhD, Prof Gabriel M Leung, MD. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study.SummaryBackgroundSince 31 Dec 2019, the Chinese city of Wuhan has reported an outbreak of atypical pneumonia caused by the 2019 novel coronavirus (2019-nCoV). Cases have been exported to other Chinese cities, as well as internationally, threatening to trigger a global
Coronavirus -- ChinaRecently, some medical institutions found that many of the pneumonia cases received were related to South China Seafood City. After receiving the report, the Municipal Health and Health Commission immediately launched a case search and retrospective investigation related to South China Seafood City in the city's medical health institutions; 27 cases have been found, of which 7 are in serious condition, and the remaining cases are stable and controllable. Two patients are expected to be
Coronavirus -- ChinaCitation:Qun Li, M. Med., Xuhua Guan, PhD, Peng Wu, PhD, Xiaoye Wang, Lei Zhou, M.Med., Yeqing Tong, et al.: Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. New England Journal of Medicine. 2020; DOI: 10.1056/NEJMoa2001316AbstractBackgroundThe initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, Hubei province, China, in December 2019 and January 2020. We analyzed data on the 1st 425 confirmed cases in
Julien Riou and Christian L. Althaus
Since December 2019, China has been experiencing a large outbreak of a novel coronavirus (2019-nCoV) which can cause respiratory disease and severe pneumonia. We estimated the basic reproduction number R0 of 2019-nCoV to be around 2.2 (90% high density interval: 1.4–3.8), indicating the potential for sustained human-to-human transmission. Transmission characteristics appear to be of similar magnitude to severe acute respiratory syndrome-related coronavirus (SARS-CoV) and pandemic influenza, indicating a risk of global spread.
Coronavirus -- China840 new cases of pneumonia caused by new coronavirus infection were added in Hubei Province (315 in Wuhan, 33 in Huangshi, 23 in Shiyan, and new [sic?] in Xiangyang). 61 new cases, 12 new cases in Yichang, 30 new cases in Jingzhou, 28 new cases in Jingmen, 27 new cases in Ezhou, 101 new cases in Xiaogan City, 111 new cases in Huanggang City, 21 new cases in Xianning City (46 cases in Suizhou City, 13 cases in Enshi Prefecture, 5 cases in Xiantao City, 11 cases in Tianmen City, 1 case in
Coronavirus -- ChinaOn [31 Dec 2019], WHO was informed of cases of pneumonia of unknown etiology (unknown cause) detected in Wuhan City, Hubei province of China. A novel coronavirus (2019-nCoV) was identified as the causative virus by Chinese authorities on [7 Jan 2020].Investigations are ongoing to evaluate the source of the outbreak, mode(s) of transmission, and the extent of infection. Available evidence on the 2019-nCoV virus and previous experience with other coronavirus (MERS-CoV and SARS-CoV) and other
Irene Galani, Ilias Karaiskos, Maria Souli, Vassiliki Papoutsaki, Lamprini Galani, Aikaterini Gkoufa, Anastasia Antoniadou and Helen Giamarellou
From September to October 2019, seven patients colonised or infected with a ceftazidime-avibactam (CZA)-resistant Klebsiella pneumoniae carbapenemase (KPC)-2-producing K. pneumoniae were detected in two intensive care units of a Greek general hospital. The outbreak strain was sequence type (ST)147 and co-produced KPC-2 and the novel plasmid-borne Vietnamese extended-spectrum β-lactamase (VEB)-25 harbouring a K234R substitution associated with CZA resistance. Epidemiological investigations revealed that the resistance was probably acquired by horizontal transmission independently from previous CZA exposure.
Coronavirus -- ChinaAs of 24:00 on [22 Jan 2020], our committee had received a total of 571 confirmed cases of pneumonia of new coronavirus infection in 25 provinces (autonomous regions, municipalities) in China, including 95 severe cases and 17 deaths (all from Hubei Province). A total of 393 suspected cases were reported in 13 provinces (autonomous regions and municipalities).At 00:00 on [22 Jan 2020] 24 provinces (autonomous regions and municipalities) reported 131 new confirmed cases and 8 new deaths, of
Coronavirus -- ChinaAt 00:00 on [20 Jan 2020, our committee received 77 new cases of pneumonia diagnosed with new type of coronavirus infection in 3 domestic provinces (regions, municipalities) (72 in Hubei Province, 2 in Shanghai, and 3 in Beijing). Cases); 27 new suspected cases were reported in 9 provinces (districts, cities) (4 in Guangdong, 1 in Sichuan, 1 in Yunnan, 7 in Shanghai, 10 in Zhejiang, 1 in Anhui, and Hainan). 1 case, 1 case in Guizhou Province, and 1 case in Ningxia Hui Autonomous Region).As
Coronavirus -- ChinaSecond case of imported new coronavirus pneumonia confirmed in Shanghai. The patient is a 35-year-old male resident in Shanghai. He went to Wuhan on the evening of [8 Jan 2020] and returned to Shanghai on [11 Jan 2020]. He developed fever, cough, and runny nose. He was admitted to the hospital for isolation and treatment after attending a fever clinic on [16 Jan 2020]. After detection by the city's disease control department, the new coronavirus nucleic acid test result was positive. Expert
A Washington state man returning from Wuhan, the outbreak's epicenter, was hospitalized in good condition. The newly discovered virus can cause coughing, fever, breathing difficulty, and pneumonia.
Coronavirus -- ChinaAn unexplained pneumonia in China caused the Korean quarantine authorities to strengthen the quarantine, and a fever-sensing camera is installed to monitor the body temperature of Chinese tourists who entered Korea at Incheon Port 1 International Passenger Terminal. Pneumonia confirmed by the new coronavirus, which is prevalent in Wuhan, China, was confirmed for the first time on [20 Jan 2020]. According to health officials, a Chinese woman, A, who arrived at Incheon International Airport
Coronavirus -- ChinaOn [18 Jan 2020], 0 cases were cured, 5 cases were discharged, 59 cases were newly added, and 1 died. On [19 Jan 2020], 0-22 hours, 1 case was discharged, and 77 cases were newly added.On the basis of continuously regulating the operation of pre-screening and triage of all types of medical institutions at all levels, our city has further increased the screening of suspected cases of pneumonia due to new coronavirus in accordance with the newly revised pneumonia diagnosis and treatment plan
Coronavirus -- ChinaIssuing authority: Wuhan City health committeeOn [17 Jan 2020], national and provincial experts screened some cases of unexplained pneumonia that were screened by community health service centers in the city and found and treated [these cases] in various hospitals based on their clinical manifestations, epidemiological history, and optimization. The positive results of the novel coronavirus nucleic acid detected by the subsequent detection kit were comprehensively judged, and 17 cases of
Coronavirus -- ChinaMinistry of Public Health screening for travelers from Wuhan City, People's Republic of China found confirmed coronavirus pneumonia of the 2019 strain from a 2nd individual, which is currently under medical supervision at Bamrasnaradura Institute waiting for the results of repeated lab tests. There has been no outbreak of the new strain of the coronavirus in Thailand.Today ([17 Jan 2020]) at the Department of Disease Control of the Ministry of Public Health in Nonthaburi Province, Dr.
Michael L Beeton, Xu-Sheng Zhang, Søren A Uldum, Cécile Bébéar, Roger Dumke, Karolina Gullsby, Margareta Ieven, Katherine Loens, Ran Nir-Paz, Sabine Pereyre, O Brad Spiller, Victoria J Chalker and the ESCMID Study Group for Mycoplasma and Chlamydia Infections (ESGMAC) Mycoplasma pneumoniae subgroup
Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia, with large epidemics previously described to occur every 4 to 7 years.
To better understand the diagnostic methods used to detect M. pneumoniae; to better understand M. pneumoniae testing and surveillance in use; to identify epidemics; to determine detection number per age group, age demographics for positive detections, concurrence of epidemics and annual peaks across geographical areas; and to determine the effect of geographical location on the timing of epidemics.
A questionnaire was sent in May 2016 to Mycoplasma experts with national or regional responsibility within the ESCMID Study Group for Mycoplasma and Chlamydia Infections in 17 countries across Europe and Israel, retrospectively requesting details on M. pneumoniae-positive samples from January 2011 to April 2016. The Moving Epidemic Method was used to determine epidemic periods and effect of country latitude across the countries for the five periods under investigation.
Representatives from 12 countries provided data on M. pneumoniae infections, accounting for 95,666 positive samples. Two laboratories initiated routine macrolide resistance testing since 2013. Between 2011 and 2016, three epidemics were identified: 2011/12, 2014/15 and 2015/16. The distribution of patient ages for M. pneumoniae-positive samples showed three patterns. During epidemic years, an association between country latitude and calendar week when epidemic periods began was noted.
An association between epidemics and latitude was observed. Differences were noted in the age distribution of positive cases and detection methods used and practice. A lack of macrolide resistance monitoring was noted.
E. Voulgari, S.D. Kotsakis, P. Giannopoulou, E. Perivolioti, L.S. Tzouvelekis and V. Miriagou
Two ceftazidime-avibactam (CAZ-AVI)-resistant Klebsiella pneumoniae carbapenemase (KPC)-positive K. pneumoniae strains, including one pandrug resistant, were isolated in 2019 from two Greek hospitals. The strains were sequence types (ST)s 258 and 147 and both harboured similar self-transmissible IncA/C2 plasmids encoding a novel Lys234Arg variant of the Vietnamese extended-spectrum β-lactamase (VEB)-1, not inhibited by AVI (VEB-25). Conjugal transfer of VEB-25-encoding plasmids to Escherichia coli yielded CAZ-AVI-resistant clones, supporting that VEB-25 is directly linked to the derived phenotype.
Coronavirus -- ChinaAt 04:00 on [15 Jan 2020], there were no new cases of pneumonitis infected with new coronavirus in our city. A total of 5 patients were discharged from the hospital and 1 new death was reported. The deceased, a male, 69 years old, became ill on [31 Dec 2019], became worse on [4 Jan 2020] and was transferred to Wuhan Jinyintan Hospital for treatment. He was admitted with severe myocarditis (myocardial enzymes reached 20 times normal, electrocardiographic abnormalities); abnormal renal function;
Coronavirus -- ChinaThursday, [16 Jan 2020][Reference]Health Bureau Tuberculosis Infectious Disease SectionOffice of Infectious Disease Information ManagementOn [14 Jan 2020], a medical institution in Kanagawa Prefecture reported a case of pneumonia to a public health center under [its] jurisdiction [in an individual who had been in Wuhan, Hubei Province, China]. About this person, when he visited a medical institution on [6 Jan 2020], a report of his stay history in Wuhan was made. It was reported
International Liver Congress (ILC) 2020
27.08.2020 - 29.08.2020
World Sepsis Day
Det 8. videnskabelige nationale møde om infektiøs endokarditis
International Congress for Tropical Medicine and Malaria (ICTMM) 2020
20.09.2020 - 24.09.2020
Meeting of the European Society for Immunodeficiencies (ESID) 2020
14.10.2020 - 17.10.2020
COVID-19 retningslinje (2020)
National handlingsplan for antibiotika til mennesker (2017)
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Infections in Patients Colonized with Extended-Spectrum Beta-Lactamase-Producing Enterobacterales – a Retrospective Cohort Study
30.07.2020Clinical Infectious Diseases Advance Access
Effectiveness of Cloth Masks for Protection Against Severe Acute Respiratory Syndrome Coronavirus 2
22.07.2020Emerging Infectious Diseases Journal
Coronavirus Disease among Persons with Sickle Cell Disease, United States, March 20–May 21, 2020
22.07.2020Emerging Infectious Diseases Journal
COVID-19: the worst may be yet to come
First step in a new era for treatment of patients with vitiligo
Hvorfor synes Professor Jens Lundgren, at du bør læse"Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV."?
Hvad tænker Professor Troels Lillebæk om"The global prevalence of latent tuberculosis: a systematic review and meta-analysis."?
Hvad synes Professor Lars Østergaard om"Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial."?
Hvad tænker Professor Thomas Benfield om"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvad synes Professor Niels Obel om"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
© 2020 Dansk Selskab for Infektionsmedicin
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