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Dokumenter [2] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [+20]
Dokumenter [2]
Version 1, oktober 2024. Denne guideline omfatter konkret håndtering af mistænkte og bekræftede tilfælde af mpox med det formål at diagnosticere mpox, behandle tilfældet samt forebygge smittespredning samt forholdsregler ifm. vaccination mod infektionen.
Nyt fra tidsskrifterne [+20]
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Emerg Microbes Infect
2.05.2025
Volume 14, Issue 1, December 2025 .
Current Opinion in Infectious Diseases
1.05.2025
Purpose of review . This review focuses on the temporal relationship between the discontinuation of the global smallpox eradication effort with the rise of mpox in Africa and worldwide. It also discusses the global 2022 clade II mpox epidemic and the current 2024 clade I mpox outbreak. Newer findings on viral evolution and pathogenesis, plus current and future strategies for disease prevention, are reviewed. Recent findings .
Journal of Medical Virology
28.04.2025
Journal of Medical Virology, Volume 97, Issue 5, May 2025.
Clinical Microbiology and Infection
26.04.2025
The immunological signature of mpox Clade IIb was described in the early stages of infection. We aimed to characterize the kinetics of both humoral and cellular immune responses against mpox from the onset of symptoms up to one year later.
BMC Infectious Diseases
16.04.2025
Mpox, previously known as monkeypox, is a zoonotic viral disease caused by the Mpox virus (MPXV), a member of the Orthopoxvirus genus. This disease is of significant concern due to its zoonotic transmission, which can be challenging to control, its ability to spread easily from person to person, the potential for severe symptoms or even fatality, and its history of frequent global outbreaks.
BMC Infectious Diseases
16.04.2025
In August 2024, the Africa CDC and WHO declared Mpox a Public Health Emergency of Continental Security and a Public Health Emergency of International Concern, respectively, following a devastating global outbreak driven by newly emerged virulent clades I (Ia, IIb) and II (IIa, IIb) of the Mpox virus.
Lancet Microbe
1.04.2025
With additional benefits over current serological assays, we believe this assay will provide substantial insight into the current global outbreak of mpox. MpoxPlex shows use for both serosurveillance and immunological studies of vaccination and infection.
Emerg Microbes Infect
29.03.2025
Volume 14, Issue 1, December 2025 .
BMC Infectious Diseases
27.03.2025
The daily surge in cases in many nations has made the growing number of human monkeypox (Mpox) cases an important global concern. Therefore, it is imperative to identify Mpox early to prevent its spread. The majority of studies on Mpox identification have utilized deep learning (DL) models. However, research on developing a reliable method for accurately detecting Mpox in its early stages is still lacking.
Emerg Microbes Infect
26.03.2025
Volume 14, Issue 1, December 2025 .
Lancet Infectious Diseases
19.03.2025
MVA-BN vaccination was safe and well tolerated. One dose of MVA-BN offered protection against mpox but effectiveness was reduced in people living with HIV. Although randomised controlled trials remain the preferred approach for assessing vaccine efficacy, combining prospective and retrospective study designs can be valuable during dynamic public health emergencies.
Emerg Microbes Infect
19.03.2025
Volume 14, Issue 1, December 2025 .
Proceedings of the National Academy of Sciences
14.03.2025
Proceedings of the National Academy of Sciences, Volume 122, Issue 10, March 2025. SignificanceMpox virus (MPXV) F8–A22–E4 polymerase holoenzyme is responsible for the accurate replication of the viral genome. Unlike other DNA polymerases, MPXV polymerase holoenzyme harbors the multifunctional cofactor A22–E4 which plays roles in .
American Journal of Tropical Medicine and Hygiene
6.03.2025
. . Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 112 Issue: 3 Pages: 677-681. .
Current Opinion in Infectious Diseases
27.02.2025
Purpose of review . The 2024 mpox outbreak, primarily driven by the possibly more virulent clade Ib strain, prompted the WHO declaring it a public health emergency of international concern (PHEIC) on August 14, 2024. This review provides essential guidance for clinicians managing mpox cases, as it contrasts the features of the 2024 outbreak with those of the 2022 epidemic to support better clinical decision-making. Recent findings .
Clinical Infectious Diseases
22.02.2025
Abstract . Background . This randomized controlled trial provided LC16m8 pre-exposure prophylaxis to high-risk individuals to assess its efficacy for mpox prevention, safety, and immunogenicity.Methods . This multicenter, randomized, open-label trial enrolled men and women aged ≥18 years at high risk of mpox. Participants were randomly assigned 1:1 to early- or late-vaccination groups. The primary endpoint was vaccine efficacy (VE) against mpox.
Lancet
14.02.2025
Clade Ib infections in Kamituga showed distinct clinical patterns compared with clade Ia outbreaks elsewhere in the country and the global clade IIb outbreak. In adults, the disease primarily affected the genito-urinary system, compatible with sexual transmission, whereas children mostly manifested extragenital lesions.
Nature
12.02.2025
Journal of Infectious Diseases
11.02.2025
Abstract . Several African countries, mainly the Democratic Republic of Congo, Burundi, and Uganda, are facing highly transmissible mpox clade Ib epidemics, prompting the World Health Organization to declare a Public Health Emergency of International Concern. It has spread to key travel hubs like Kinshasa, Bujumbura, and Kampala, increasing international spread risks.
Clinical Infectious Diseases
8.02.2025
Aktuelle smitsomme sygdomme [+20]
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ProMED
12.04.2025
. . . MPOX - KENYA (03): UPDATE, VACCINE. **********************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 10 Apr 2025 . Source: Nation Africa [edited] . nation.africa/kenya/health/mpox-vaccination-planned-in-13-high-risk-counties-4997632 . . . Kenya will soon launch its first mpox vaccination campaign in 13.
Medscape Infectious Diseases
9.04.2025
Britain's health security agency said on Monday another case of the mpox variant clade lb had been detected in England in a person who had no reported travel history or link. . Reuters Health Information
Medscape Infectious Diseases
2.04.2025
Denmark's Bavarian Nordic said on Monday the U.S. Food and Drug Administration has approved a freeze-dried formulation of its mpox and smallpox vaccine. . Reuters Health Information
Medscape Infectious Diseases
1.04.2025
The modified vaccinia Ankara-Bavarian Nordic vaccine, originally approved for smallpox, is safe and well tolerated in at-risk individuals, with one dose offering protection against mpox. . Medscape News UK
ProMED
29.03.2025
. . . MPOX - DEMOCRATIC REPUBLIC OF CONGO: (TANGANYIKA) SUSPECTED. ***********************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 27 Mar 2025 . Source: Focus on Africa [edited] . www.focusonafrica.info/en/drc-over-240-suspected-cases-of-mpox-in-moba-in-the-first-three-months-of-2025/ . . .
ProMED
25.03.2025
. . . MPOX - UGANDA: (KITGUM) SUSPECTED CASES. ***************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Sun 23 Mar 2025 . Source: The Independent [edited] . www.independent.co.ug/mpox-kitgum-reports-12-suspected-cases-in-children/ . . . Twelve suspected cases of Mpox have been reported in children in. Namokora Town Council, Kitgum District. .
ProMED
25.03.2025
. . . MPOX - PAKISTAN (02): (SINDH). *****************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Sat 22 Mar 2025 19:22 PKT . Source: 24 NewsTV [edited] . 24newshd.tv/22-Mar-2025/first-monkeypox-case-confirmed-in-karachi . . . A 29-year-old man has tested positive for [mpox], marking the city's. [Karachi] first confirmed case. .
ECDC Epidemiological Update
18.03.2025
Every month ECDC provides detailed epidemiological overview of the worldwide transmission of mpox in its weekly threat report.
ProMED
10.03.2025
. . . MPOX - BRAZIL: (SAO PAULO) CLADE 1B. ***********************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Sat 8 Mar 2025 17:01 BRT . Source: Diario de Salud [in Spanish, machine trans., edited] . www.diariodesalud.com.do/texto-diario/mostrar/5209200/confirman-primer-caso-nueva-cepa-mpox-brasil . . .
ProMED
10.03.2025
. . . MPOX - PAKISTAN: (KHYBER PAKHTUNKHWA) ex SAUDI ARABIA. *****************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 7 Mar 2025 . Source: Ary News [edited] . arynews.tv/monkeypox-pakistan-reports-two-more-case-in-2025/ . . . Pakistan has reported 2 more [mpox] cases in 2025, ARY News reported. .
Medscape Infectious Diseases
28.02.2025
The mpox outbreak is still a public health emergency, the World Health Organization said on Thursday. . Reuters Health Information
ProMED
16.02.2025
. . . MPOX - KENYA (02): (BUSIA) THREE NEW CASES, CONFIRMED. *****************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 14 Feb 2025 . Source: Standard [edited] . www.standardmedia.co.ke/health/health-science/article/2001511792/kenya-confirms-three-new-mpox-cases . . .
ProMED
16.02.2025
. . . MPOX - UAE: ex UGANDA, FIRST CASE, CLADE 1B, WHO. ************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 14 Feb 2025 . Source: Geo News [edited] . www.geo.tv/latest/590591-uae-reports-first-case-of-new-clade-1b-mpox-says-who . . . The World Health Organisation (WHO) reported on Thursday [13 Feb 2025].
ProMED
14.02.2025
. . . MPOX - USA (02): (NEW YORK) CLADE IB. ************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Tue 11 Feb 2025 . Source: Reuters [edited] . www.reuters.com/business/healthcare-pharmaceuticals/new-york-health-department-confirms-first-case-new-mpox-strain-2025-02-11/ . . . New York health department confirms 1st case of new mpox strain .
Medscape Infectious Diseases
13.02.2025
The U.S Centers for Disease Control and Prevention said on Wednesday that a person diagnosed with clade1b mpox in New York was currently in isolation and that it was trying. . Reuters Health Information
Medscape Infectious Diseases
13.02.2025
The New York State Department of Health on Tuesday confirmed its first case of the new mpox strain, adding to the global concerns over the spread of the little-known. . Reuters Health Information
ProMED
12.02.2025
. . . MPOX - IRELAND: CLADE 1, IMPORTED, FIRST CASE. *********************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 7 Feb 2025 . Source: Health Service Executive (HSE) [edited] . about.hse.ie/news/hse-confirms-single-case-of-clade-i-mpox-in-ireland/ . . . The HSE has detected one imported case of clade 1 mpox. The Irish.
ProMED
12.02.2025
. . . MPOX - USA: (NEW HAMPSHIRE) CLADE 1, IMPORTED, THIRD CASE. *********************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 7 Feb 2025 . Source: New Hampshire Department of Health and Human Services. [edited] . www.dhhs.nh.gov/news-and-media/dhhs-identifies-new-hampshire-resident-clade-i-mpox . . .
ProMED
10.02.2025
. . . MPOX - SOUTH SUDAN (01): (CENTRAL EQUATORIA) OUTBREAK DECLARED. **************************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Fri 7 Feb 2025 . Source: Radio Tamazuj [edited] . www.radiotamazuj.org/en/news/article/mpox-outbreak-declared-in-south-sudan . . .
ProMED
9.02.2025
. . . MPOX - CHINA (02): (HONG KONG) UNDERLYING HEALTH CONDITIONS. ***********************************************************. A ProMED-mail post. www.promedmail.org. ProMED-mail is a program of the. International Society for Infectious Diseases. www.isid.org . Date: Thu 6 Feb 2025 . Source: The Standard [edited] . www.thestandard.com.hk/breaking-news/section/4/226906/Health-authorities-probe-confirmed-Mpox-Case . . .