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Søgning på udtrykket 'antibiotic stewardship' giver 23 resultater
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Telemedicine interventions for improving antibiotic stewardship and prescribing: A systematic review
PLoS One Infectious Diseases
3.04.2025
…anath Tiwary . The global antibiotic resistance crisis necessitates optimized stewardship programs, with telemedicine emerging as a promising delivery strategy. This systematic review evaluated the effectiveness of telemedicine interventions in improving antibiotic stewardship across clinical settings. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically searched seven databases from January 2010 to July 2024.
Clinical Infectious Diseases
24.11.2024
BMC Infectious Diseases
23.04.2025
…and the need for stricter food safety measures and antibiotic stewardship programs. These findings highlight the public health risks of STEC contamination in food products, particularly traditional ice cream and juice. Localized studies are essential to understand specific risks and inform targeted interventions. Strategies such as improved hygiene practices, stringent food safety regulations, and effective antibiotic stewardship programs are critical to mitigating the threat posed by STEC in food products.
BMC Infectious Diseases
19.04.2025
…-escalated (P > 0.05). . Conclusions. The study underscores the challenges of implementing effective antibiotic stewardship in UTI management, particularly regarding carbapenem de-escalation. Enhanced protocols and clinician education are essential to optimize de-escalation practices, especially in cases with negative microbiological results. Further research is needed to refine these strategies and address the growing issue of antibiotic resistance in UTIs.
BMC Infectious Diseases
17.04.2025
…ecular-based MG testing would identify 14.8% (16/108) as positive, capturing 69.6% (16/23) of all symptomatic MG mono-infections. . Conclusions. MG was common among outpatients and frequently co-occurred with CT, NG, and TV infections. Syndromic case management often misclassified MG infections, leading to ineffective treatment. Expanding molecular-based MG testing could enhance antibiotic stewardship, crucial for preventing the spread of drug-resistant strains.
Infection
17.04.2025
. Purpose. Antimicrobial resistance increases with the use of broad-spectrum antibiotics. Studies evaluating antibiotic stewardship are in high demand. Is piperacillin/tazobactam non-inferior to carbapenems regarding 30-day mortality among patients with bloodstream infections caused by extended-spectrum beta-lactamase-producing Enterobacterales?. . Methods.
Clinical Infectious Diseases
12.04.2025
…al for patients with septic shock or multiorgan dysfunction but short delays can safely be tolerated by patients with single organ dysfunction without shock. This allows time to clarify whether these patients are infected or not. We suggest modifying sepsis operational definitions to flag just those patients in whom short antibiotic delays are associated with worse outcomes. This will help focus sepsis care where it is needed, aid antibiotic stewardship, and increase the validity of sepsis quality measures.
JAMA Network Open New Online
10.04.2025
Increasing antibiotic resistance is an urgent public health threat, and antibiotic stewardship is an important strategy for mitigating this threat. Antibiotic stewardship programs strive to improve patient safety by optimizing the use of antibiotics that are indicated and reducing unnecessary antibiotic use.
BMC Infectious Diseases
6.04.2025
… UTIs remain a significant health concern among females at Zomba Central Hospital, particularly in the reproductive age group. The high prevalence of multidrug-resistant uropathogens, especially against commonly used antibiotics like ampicillin and ceftriaxone, underscores the urgent need for regular antimicrobial resistance surveillance and evidence-based antibiotic stewardship to guide effective treatment strategies. . Clinical trial number. Not applicable.
BMJ Open
14.03.2025
. Objectives. To analyse, compare and present the 10-year diagnosis-specific antibiotic prescribing trends for paediatric inpatients at a non-teaching hospital (NTH) and a teaching hospital (TH) in India. . Design and setting. A prospective, observational study of antibiotic prescriptions in paediatric departments of two private-sector hospitals in central India. Inpatients were grouped into clinically confirmed infections, suspected infections and no infections. . Outcomes.
Current Opinion in Infectious Diseases
27.02.2025
… evidence indicates that few patients receive guideline concordant empiric antibiotics and appropriate duration in the United States, although this likely can be extrapolated to other countries. One of the most commonly identified opportunities to improve antibiotic stewardship is duration of therapy more than 10 days.
Current Opinion in Infectious Diseases
27.02.2025
…he setting of appropriate clinical response, is a reasonable strategy to reduce costs and selective pressure driving antimicrobial resistance. This was demonstrated in the latest REGARD-VAP study, even among VAP patients with nonfermenting Gram-negative bacilli or carbapenem-resistant pathogens. Given the challenges in diagnosing VAP, such pragmatic approaches would be essential as part of overall antibiotic stewardship programmes. Further refinement to the criteria for antibiotic cessation may be possible.
Infection
13.02.2025
. Abstract. . Purpose. Elevations in inflammatory markers after transcatheter aortic valve replacement (TAVR) often lead to preemptive antibiotic therapy (ABT). Distinguishing between physiological inflammatory reaction and true infection is crucial for rational ABT use. . . . Methods.
BMC Infectious Diseases
1.02.2025
…resistance rates, even if antibiotic use patterns remain unchanged. . . . Conclusion. This study emphasizes the importance of regular monitoring of respiratory pathogen distribution and antimicrobial resistance patterns and the need for a comprehensive approach to managing RTIs, including implementation of antibiotic stewardship programs, infection control measures, and development of new therapies. . .
Journal of the American Medical Association
29.01.2025
A multicountry clinical trial published in the New England Journal of Medicine found a 1-week course of antibiotics to be equally effective in treating bloodstream infections as a 2-week regimen, a promising result for those seeking to foster antibiotic stewardship as part of growing efforts to curb antimicrobial resistance.
Infection
24.01.2025
…iate antibiotic therapy was associated with survival, whereas antibiotic resistance and organ infection were associated with a fatal outcome. . . . Conclusion. Prior antibiotic exposure in hematological patients is associated with resistance in PABSI, which is a major risk factor for a fatal outcome. Antibiotic stewardship efforts should be intensified and fluoroquinolone prophylaxis needs to be reconsidered. . .
BMC Infectious Diseases
3.01.2025
… . Conclusion. The present study indicates an association between multidrug resistance in P. aeruginosa and its biofilm formation capabilities. Additionally, over half of the isolates were resistant to multiple drugs, with prior use of ciprofloxacin linked to the development of multidrug-resistance. These findings suggest that antibiotic stewardship programs in hospital settings may be beneficial in addressing resistance. . .
BMC Infectious Diseases
1.12.2024
…. . Conclusion. In conclusion, this study highlights the alarming prevalence of antimicrobial resistance in Arcobacter spp. Monitoring Arcobacter spp. resistance can be achieved through surveillance, risk assessments, antibiotic stewardship in agriculture, public education, research collaborations, rapid diagnostics, and harmonized policies, all aimed at reducing contamination and safeguarding public health effectively. . .
PLoS One Infectious Diseases
27.11.2024
…I: 1.10–2.19, p-value = 0.012) and 1.93 times higher odds of using multiple antibiotics (aOR:1.93, 95% CI: 1.23–3.02, p-value = 0.004) compared to children with non-bloody diarrhea. Conclusion The study underscores the excessive use of antimicrobials among children with diarrheal illnesses. It is also evident that metronidazole use and multiple antibiotic use are increasing among children due to bloody diarrhea, which is alarming and calls for antibiotic stewardship by regulating bodies in the country.
BMC Infectious Diseases
14.09.2024
…nical isolates in a private tertiary hospital in Southwestern Nigeria, with 44% and 18% of isolates harboring these genes, respectively. Notably, 46% of isolates were resistant to carbapenems despite lacking these genes, suggesting alternative resistance mechanisms. The findings underscore the urgent need for enhanced surveillance, infection control measures, and antibiotic stewardship programs to combat the spread of multidrug-resistant Klebsiella pneumoniae in healthcare settings. . .
Aktuelle smitsomme sygdomme [3]
Aktuelle smitsomme sygdomme [3]
Medscape Infectious Diseases
4.03.2025
Rapid syndromic polymerase chain reaction testing in the ICU vs standard-of-care testing improves antibiotic stewardship but fails to demonstrate non-inferiority in the clinical cure of pneumonia within 14 days. . Medscape News UK
Eurosurveillance latest updates
15.11.2024
. Background. Antibiotic resistance poses a considerable public health threat, with data-driven stewardship a main prevention measure. While quantifying antibiotic consumption is a key component of antibiotic stewardship programmes, the choice of denominator for calculating this metric can impact comparative analyses and trend evaluations substantially, influencing targeted stewardship interventions. . . Aim.
Eurosurveillance latest updates
13.09.2024
…s. Broad-spectrum penicillins, tetracyclines and macrolides were the most prescribed antibiotic classes. . . Conclusion. Primary care contributed considerably less to AMC than anticipated, and hospital-affiliated outpatient care emerged as an important prescriber. Surveillance at the prescriber level enables the identification of prescribing patterns within all prescriber groups, offering unprecedented visibility and allowing a more targeted antibiotic stewardship according to prescriber groups. . . .