Søgeord (pneumoni) valgt.
11 emner vises.
1
Emergence of OXA-48-like producing Citrobacter species, Germany, 2011 to 2022
Julian Sommer, Hannah Reiter, Janko Sattler, Elisabetta Cacace, Jessica Eisfeld, Sören Gatermann, Axel Hamprecht and Stephan Göttig
Eurosurveillance latest updates, 12.04.2024
Tilføjet 12.04.2024
BackgroundCarbapenemase-producing Enterobacterales are a public health threat worldwide and OXA-48 is the most prevalent carbapenemase in Germany and western Europe. However, the molecular epidemiology of OXA-48 in species other than Escherichia coli and Klebsiella pneumoniae remains poorly understood. AimTo analyse the molecular epidemiology of OXA-48 and OXA-48-like carbapenemases in Citrobacter species (spp.) in Germany between 2011 and 2022. MethodsData of 26,822 Enterobacterales isolates sent to the National Reference Centre (NRC) for Gram-negative bacteria were evaluated. Ninety-one Citrobacter isolates from 40 German hospitals harbouring blaOXA-48/OXA-48‑like were analysed by whole genome sequencing and conjugation experiments. ResultsThe frequency of OXA-48 in Citrobacter freundii (CF) has increased steadily since 2011 and is now the most prevalent carbapenemase in this species in Germany. Among 91 in-depth analysed Citrobacter spp. isolates, CF (n = 73) and C. koseri (n = 8) were the most common species and OXA-48 was the most common variant (n = 77), followed by OXA-162 (n = 11) and OXA‑181 (n = 3). Forty percent of the isolates belonged to only two sequence types (ST19 and ST22), while most other STs were singletons. The plasmids harbouring blaOXA‑48 and blaOXA-162 belonged to the plasmid types IncL (n = 85) or IncF (n = 3), and plasmids harbouring blaOXA‑181 to IncX3 (n = 3). Three IncL plasmid clusters (57/85 IncL plasmids) were identified, which were highly transferable in contrast to sporadic plasmids. ConclusionIn CF in Germany, OXA-48 is the predominant carbapenemase. Dissemination is likely due to distinct highly transmissible plasmids harbouring blaOXA‑48 or blaOXA-48-like and the spread of the high-risk clonal lineages ST19 and ST22.
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2
Ongoing measles outbreak, the Federation of Bosnia and Herzegovina, December 2023 to February 2024
Sanjin Musa, Irma Salimović-Bešić, Jasmina Brkić Džambić, Nijaz Tihić, Anisa Bajramović, Suzana Arapčić, Amela Dedeić-Ljubović and Siniša Skočibušić
Eurosurveillance latest updates, 1.03.2024
Tilføjet 1.03.2024
We report on an ongoing measles outbreak in the Federation of Bosnia and Herzegovina with 141 cases notified between week 52 2023 and week 6 2024. Among those with known vaccination status, 97% were unvaccinated and the most affected group is children under the age of 5 years (n = 87) who were not vaccinated during the pandemic years. Sixty-eight cases were hospitalised, the most common complications were measles-related pneumonia and diarrhoea. The sequenced measles viruses from four cases belonged to genotype D8.
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3
Notes from the Field: Reemergence of Mycoplasma pneumoniae Infections in Children and Adolescents After the COVID-19 Pandemic, United States, 2018-2024
Morbidity and Mortality Weekly Report (MMWR), 22.02.2024
Tilføjet 22.02.2024
This report describes an increase in Mycoplasma pneumoniae, a common cause of respiratory illness, beginning in fall 2023.
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4
Hypervirulent Resistant K pneumoniae On the Rise in EU
Medscape Infectious Diseases, 15.02.2024
Tilføjet 15.02.2024
The ECDC has called for mitigating actions in the face of more European Union and European Economic Area countries reporting hypervirulent Klebsiella pneumoniae ST23. Medscape Medical News
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5
Europe Approves Exblifep for UTIs and Pneumonia
Medscape Infectious Diseases, 26.01.2024
Tilføjet 26.01.2024
Exblifep is as effective as piperacillin-tazobactam in the treatment of complicated urinary tract infections, the European Medicines Agency said. Medscape Medical News
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6
Increased incidence of Mycoplasma pneumoniae infections and hospital admissions in the Netherlands, November to December 2023
Dita C Bolluyt, Sjoerd M Euser, Dennis Souverein, Annemarie MC van Rossum, Jayant Kalpoe, Mireille van Westreenen, Marco Goeijenbier, Dominic Snijders, Dirk Eggink, Femke Jongenotter, Steven FL van Lelyveld and Marlies A van Houten
Eurosurveillance latest updates, 26.01.2024
Tilføjet 26.01.2024
Mycoplasma pneumoniae is an important cause of pneumonia and extra-pulmonary manifestations. We observed a rise in admissions due to M. pneumoniae infections starting October 2023 in a regional hospital in the Netherlands and an increased incidence in national surveillance data. The incidence in the Netherlands has not been that high since 2011. The patients had a lower median age compared with 2019 and 2020 (28 vs 40 years). M. pneumoniae should be considered in patients with respiratory symptoms, especially children.
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7
Toothbrushing in Hospital Reduces Infections and Death
Medscape Infectious Diseases, 12.01.2024
Tilføjet 12.01.2024
Daily toothbrushing was associated with a 33% reduction in risk for hospital-acquired pneumonia among inpatients, according to a recent analysis. Medscape Medical News
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8
Increase of respiratory illnesses among children in Beijing, China, during the autumn and winter of 2023
Cheng Gong, Fang Huang, Luodan Suo, Xuejiao Guan, Lu Kang, Hui Xie, Geng Hu, Peng Yang and Quanyi Wang
Eurosurveillance latest updates, 12.01.2024
Tilføjet 12.01.2024
In 2023, through an ongoing respiratory pathogen surveillance system, we observed from mid-September onwards, an increase of respiratory illness among children aged ≤ 15 years presenting at hospital outpatient clinics in Beijing, China. Data indicated that illness was caused by multiple pathogens, predominantly Mycoplasma pneumoniae. Seasonality, periodicity and high prevalence of resistance to macrolide (30 of 30 strains sequenced with the A2063G mutation) were important characteristics of the M. pneumoniae epidemic, which resulted in a rise in consultations at specialised paediatric hospitals.
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9
Mycoplasma pneumoniae epidemic in Denmark, October to December, 2023
Anne Christine Nordholm, Bolette Søborg, Pikka Jokelainen, Karina Lauenborg Møller, Lotte Flink Sørensen, Tyra Grove Krause, Søren Anker Uldum and Hanne-Dorthe Emborg
Eurosurveillance latest updates, 12.01.2024
Tilføjet 12.01.2024
We report a surge of patients, especially children and adolescents, with respiratory disease caused by Mycoplasma pneumoniae in Denmark since October 2023. While the surge has reached an epidemic level, no impact on hospital capacity has been observed; only 14% (446/3,195) of cases, primarily adults, required hospitalisation. Macrolide resistance was detected in less than 2% of samples tested. Timely monitoring of hospitalisations linked to M. pneumoniae infections has been established to inform the healthcare system, decisionmakers and the public.
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10
Communicable disease threats report, 3-9 December 2023, week 49
ECDC
ECDC Communicable Disease Threats Report, 8.12.2023
Tilføjet 8.12.2023
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 3-9 December 2023 and includes updates on respiratory virus epidemiology in the EU/EEA, SARS-CoV-2 variant classification, measles, mpox, Mycoplasma pneumoniae, West Nile virus, and MERS-CoV.
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11
Communicable disease threats report, 3-9 December 2023, week 49
ECDC
ECDC COVID-19 updates, 8.12.2023
Tilføjet 8.12.2023
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 3-9 December 2023 and includes updates on respiratory virus epidemiology in the EU/EEA, SARS-CoV-2 variant classification, measles, mpox, Mycoplasma pneumoniae, West Nile virus, and MERS-CoV.
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