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1
Cyclospora cayetanensis
Junqiang Li, Kaihui Zhang, Longxian Zhang
Trends in Parasitology, 2.12.2021
Tilføjet 3.12.2021
Cyclospora cayetanensis is a coccidian parasite that causes gastrointestinal symptoms only in humans. International travel and food importation from cyclosporiasis-endemic regions are linked to cyclosporiasis outbreaks, making it not only a burden on individual health but also a global public threat. Human cyclosporiasis has been identified in at least 54 countries, with the disease being most common in low-income developing countries. It is transmitted via the fecal–oral route and has both asexual and sexual development stages.
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2
Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants
Catherine J. Reynolds, Joseph M. Gibbons, Corinna Pade, Kai-Min Lin, Diana Munoz Sandoval, Franziska Pieper, David K. Butler, Siyi Liu, Ashley D. Otter, George Joy, Katia Menacho, Marianna Fontana, Angelique Smit, Beatrix Kele, Teresa Cutino-Moguel, Mala K. Maini, Mahdad Noursadeghi, COVIDsortium Immune Correlates Network‡, Tim Brooks, Amanda Semper, Charlotte Manisty,, Thomas A. Treibel,, James C. Moon,, , Áine McKnight, Daniel M. Altmann, Rosemary J. Boyton,
Science, 2.12.2021
Tilføjet 3.12.2021
3
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain
Katherine G. Nabel, Sarah A. Clark, Sundaresh Shankar, Junhua Pan, Lars E. Clark, Pan Yang, Adrian Coscia, Lindsay G. A. McKay, Haley H. Varnum, Vesna Brusic, Nicole V. Tolan, Guohai Zhou, Michaël Desjardins,, Sarah E. Turbett,, Sanjat Kanjilal,, Amy C. Sherman, Anand Dighe, Regina C. LaRocque, Edward T. Ryan,, Casey Tylek, Joel F. Cohen-Solal, Anhdao T. Darcy, Davide Tavella, Anca Clabbers, Yao Fan, Anthony Griffiths, Ivan R. Correia, Jane Seagal, Lindsey R. Baden,,, Richelle C. Charles, Jonathan Abraham,,,
Science, 2.12.2021
Tilføjet 3.12.2021
4
4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication
Julien Sourimant, Carolin M. Lieber, Megha Aggarwal, Robert M. Cox, Josef D. Wolf, Jeong-Joong Yoon, Mart Toots, Chengin Ye, Zachary Sticher, Alexander A. Kolykhalov,, Luis Martinez-Sobrido, Gregory R. Bluemling,, Michael G. Natchus, George R. Painter,,, Richard K. Plemper,
Science, 2.12.2021
Tilføjet 3.12.2021
5
Impact of community masking on COVID-19: A cluster-randomized trial in Bangladesh
Jason Abaluck, Laura H. Kwong,, Ashley Styczynski, Ashraful Haque, Md. Alamgir Kabir, Ellen Bates-Jefferys, Emily Crawford, Jade Benjamin-Chung, Shabib Raihan, Shadman Rahman, Salim Benhachmi, Neeti Zaman Bintee, Peter J. Winch, Maqsud Hossain, Hasan Mahmud Reza, Abdullah All Jaber, Shawkee Gulshan Momen, Aura Rahman, Faika Laz Banti, Tahrima Saiha Huq, Stephen P. Luby,, Ahmed Mushfiq Mobarak,
Science, 2.12.2021
Tilføjet 3.12.2021
6
How to be prepared for the future
Raina MacIntyre
Lancet Infectious Diseases, 3.12.2021
Tilføjet 3.12.2021
Global Health Security–a blueprint for the future, by Lawrence O. Gostin, is a sweeping journey across current and future issues in health security and the urgency of addressing current gaps in governance. Gostin begins with the COVID-19 pandemic, arguably the greatest global catastrophe in over 100 years, and asks the question why the world was so unprepared. He makes a compelling case for the importance of global cooperation and the risk of national interests overriding global interests in pandemic control.
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7
Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: a spatiotemporal modelling study
Christos Kokaliaris, Amadou Garba, Martin Matuska, Rachel N Bronzan, Daniel G Colley, Ameyo M Dorkenoo, Uwem F Ekpo, Fiona M Fleming, Michael D French, Achille Kabore, Jean B Mbonigaba, Nicholas Midzi, Pauline N M Mwinzi, Eliézer K N'Goran, Maria Rebollo Polo, Moussa Sacko, Louis-Albert Tchuem Tchuenté, Edridah M Tukahebwa, Pitchouna A Uvon, Guojing Yang, Lisa Wiesner, Yaobi Zhang, Jürg Utzinger, Penelope Vounatsou
Lancet Infectious Diseases, 3.12.2021
Tilføjet 3.12.2021
Our model-based estimates suggest that schistosomiasis prevalence in sub-Saharan Africa has decreased considerably, most likely explained by the scale-up of preventive chemotherapy. There is a need to consolidate gains in the control of schistosomiasis by means of preventive chemotherapy, coupled with other interventions to interrupt disease transmission.
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8
Risk Factors for SARS-CoV-2 Infection Among US Healthcare Personnel, May–December 2020
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
9
Streptococcus gallolyticus and Bacterial Endocarditis in Swine, United States, 2015–2020
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
10
Monitoring International Travelers Arriving in Hong Kong for Genomic Surveillance of SARS-CoV-2
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
11
Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
12
Limited Propagation of SARS-CoV-2 among Children in a Childcare Center, Canada, 2021
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
13
Cluster of SARS-CoV-2 Gamma Variant Infections, Parintins, Brazil, March 2021
Emerging Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
14
Transmission Dynamics of Large Coronavirus Disease Outbreak in Homeless Shelter, Chicago, Illinois, USA, 2020
Emerging Infectious Diseases, 8.10.2021
Tilføjet 2.12.2021
15
Use of Private Sector Workforce Respiratory Disease Short-Term Disability Claims to Assess SARS-CoV-2, Mexico, 2020
Emerging Infectious Diseases, 5.10.2021
Tilføjet 2.12.2021
16
Prior SARS-CoV-2 infection increases reactogenicity after SARS-COV-2 mRNA vaccine and could delay the administration of the vaccine based on timing of infection
Infection, 2.12.2021
Tilføjet 2.12.2021
17
Epidemiology and in vitro activity of ceftazidime–avibactam, meropenem–vaborbactam, imipenem–relebactam, eravacycline, plazomicin, and comparators against Greek carbapenemase-producing Klebsiella pneumoniae isolates
Infection, 2.12.2021
Tilføjet 2.12.2021
Abstract
Background
The increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) infections is of great concern because of limited treatment options. New antimicrobials were recently approved for clinical therapy. This study evaluated the epidemiology of carbapenemase-producing K. pneumoniae isolates collected at a Greek university hospital during 2017–2020, and their susceptibilities to ceftazidime–avibactam (CAZ/AVI), meropenem–vaborbactam (M/V), imipenem–relebactam (I/R), eravacycline, plazomicin, and comparators.
Methods
Minimum inhibitory concentrations (MICs) were evaluated by Etest. Only colistin MICs were determined by the broth microdilution method. Carbapenemase genes were detected by PCR. Selected isolates were typed by multilocus sequence typing (MLST).
Results
A total of 266 carbapenemase-producing K. pneumoniae strains were isolated during the 4-year study period. Among them, KPC was the most prevalent (75.6%), followed by NDM (11.7%), VIM (5.6%), and OXA-48 (4.1%). KPC-producing isolates belonged mainly to ST258 and NDM producers belonged to ST11, whereas OXA-48- and VIM producers were polyclonal. Susceptibility to tigecycline, fosfomycin, and colistin was 80.5%, 83.8%, and 65.8%, respectively. Of the novel agents tested, plazomicin was the most active inhibiting 94% of the isolates at ≤ 1.5 μg/ml. CAZ/AVI and M/V inhibited all KPC producers and I/R 98.5% of them. All OXA-48 producers were susceptible to CAZ/AVI and plazomicin. The novel β-lactam/β-lactamase inhibitors (BLBLIs) tested were inactive against MBL-positive isolates, while eravacycline inhibited 61.3% and 66.7% of the NDM and VIM producers, respectively.
Conclusions
KPC remains the predominant carbapenemase among K. pneumoniae, followed by NDM. Novel BLBLIs, eravacycline, and plazomicin are promising agents for combating infections by carbapenemase-producing K. pneumoniae. However, the emergence of resistance to these agents highlights the need for continuous surveillance and application of enhanced antimicrobial stewardship.
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18
Re: Vertebral osteomyelitis in bacterial meningitis patients
Olga Dzupova
International Journal of Infectious Diseases, 2.12.2021
Tilføjet 2.12.2021
I read with interest the original report “Vertebral osteomyelitis in bacterial meningitis patients” (Sheybani et al., 2021). The authors pointed out the possible coexistence of acute bacterial meningitis (ABM) and vertebral osteomyelitis (VO), or infective endocarditis, and the need for longer duration of antimicrobial treatment in such cases. That is correct. However, the hypothesis that VO is a complication of ABM is rather incorrect.
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